Talampanel

Product Name: Talampanel
CAS No.: 161832-65-1
Chemical Name: Talampanel
Synonyms: C13670;CS-1843;Ampanel;Kinampa;AC1L4UWP;AC1Q5KPR;LY 300164;GYKI 53773;Talampanel;Talampanel (INN)
CBNumber: CB61024197
Molecular Formula: C19H19N3O3
Formula Weight: 337.37
MOL File: 161832-65-1.mol

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Talampanel Property

Melting point:: 169-172°
alpha: D -321.34° (c = 1 in methanol)
Boiling point:: 528.9±60.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble15mg/mL, clear
form: powder
pka: 4.67±0.10(Predicted)
color: white to beige
optical activity: [α]/D -280 to -340°, c = 1 in methanol
InChIKey: JACAAXNEHGBPOQ-LLVKDONJSA-N

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Safety

Hazard Codes: T,N
Risk Statements: 25-50/53
Safety Statements: 45-60-61
RIDADR: UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0686
Product name: Talampanel
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $128
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0686
Product name: Talampanel
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $406
Updated: 2025/07/31

Cayman Chemical

Product number: 15341
Product name: Talampanel
Purity: ≥98%
Packaging: 5mg
Price: $98
Updated: 2024/03/01

Cayman Chemical

Product number: 15341
Product name: Talampanel
Purity: ≥98%
Packaging: 10mg
Price: $147
Updated: 2024/03/01

Cayman Chemical

Product number: 15341
Product name: Talampanel
Purity: ≥98%
Packaging: 25mg
Price: $245
Updated: 2024/03/01

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Talampanel Chemical Properties,Usage,Production

Uses

Talampanel is a potent and selective AMPA antagonist and is also used as an antiepileptic drug.

Definition

ChEBI: Talampanel is a member of benzodioxoles.

Biological Activity

Talampanel ia a specific noncompetitive AMPA receptor antagonist and anticonvulsant.

in vivo

Talampanel (orally administration; 5 mg/kg; once a day; 2 weeks) reduces motoneuronal calcium in a mouse model of ALS, but its efficacy declines as the disease progresses^[1].

Animal Model:	Female mutant SOD1 Tg mice^[1]
Dosage:	5 mg/kg
Administration:	Orally administration; 5 mg/kg; once a day; 2 weeks
Result:	Had a significant effect in reducing the calcium level only at the age of 12 weeks.

storage

+4°C

Talampanel Preparation Products And Raw materials

Raw materials

Preparation Products

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Talampanel Suppliers

China 56 Europe 2 United Kingdom 1 United States 14 Global 73

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4768
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Changzhou PBpharmaceutical R&D Co.,Ltd

Tel: 086-0519-83990708 18915800124
Fax: 0519-83990708
Email: info@pbpharm.com
Country: China
ProdList: 487
Advantage: 55

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

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View Lastest Price from Talampanel manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Talampanel 161832-65-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

161832-65-1, TalampanelRelated Search:

Acetyl coenzyme A sodium salt N-ACETYL-L-TYROSINE ETHYL ESTER METSULFURON METHYL Methyl salicylate 1,4-Dioxane Kresoxim-methyl Methylparaben Bensulfuron methyl Escitalopram Thiophanate-methyl (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Methyl cyclopentenolone Methyl Parathion-methyl Methyl bromide Talampanel

Talampanel

(8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

C13670

GYKI 53773

LY 300164

TalaMpanel(LY300164)

(8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine Talampanel(LY300164)

Talampanel (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

(R)-(-)-1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine

Talampanel (GYKI 53773)

CS-1843

AC1L4UWP

AC1Q5KPR

Ampanel

AMPANEL; KINAMPA; TALAMPANEL (INN); GYKI 53773; AC1L4UWP; AC1Q5KPR

Kinampa

Talampanel (INN)

7H-1,3-Dioxolo[4,5-h][2,3]benzodiazepine, 7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-, (8R)-

Talampanel >=97% (HPLC)

LY300164,GYKI 53773,inhibit,Ionotropic glutamate receptors,Talampanel,iGluR,LY 300164,Apoptosis,GYKI53773,Inhibitor

(R)-1-(5-(4-Aminophenyl)-8-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-7-yl)ethan-1-one

1-[(13R)-10-(4-aminophenyl)-13-methyl-4,6-dioxa-11,12-diazatricyclo[7.5.0.03,?]tetradeca-1,3(7),8,10-tetraen-12-yl]ethan-1-one

Talampanel, 10 mM in DMSO

161832-65-1