Pyridine, 5-bromo-2-(chloromethyl)- (9CI)
- Product Name
- Pyridine, 5-bromo-2-(chloromethyl)- (9CI)
- CAS No.
- 168823-76-5
- Chemical Name
- Pyridine, 5-bromo-2-(chloromethyl)- (9CI)
- Synonyms
- RSYY(Vorapaxar Sulfatet)-53;5-bromo-2-(chloromethyl)pyridine;Pyridine, 5-bromo-2-(chloromethyl)-;Pyridine, 5-bromo-2-(chloromethyl)- (9CI)
- CBNumber
- CB61055926
- Molecular Formula
- C6H5BrClN
- Formula Weight
- 206.47
- MOL File
- 168823-76-5.mol
Pyridine, 5-bromo-2-(chloromethyl)- (9CI) Property
- Boiling point:
- 243.4±25.0 °C(Predicted)
- Density
- 1.631±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 1.35±0.22(Predicted)
- Appearance
- Light brown to yellow Liquid
N-Bromosuccinimide Price
- Product number
- B614080
- Product name
- 5-Bromo-2-(chloromethyl)pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0366823
- Product name
- 5-BROMO-2-(CHLOROMETHYL)PYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.07
- Updated
- 2021/12/16
- Product number
- A142230
- Product name
- 5-Bromo-2-(chloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $844
- Updated
- 2021/12/16
- Product number
- CM127652
- Product name
- 5-bromo-2-(chloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $847
- Updated
- 2021/12/16
- Product number
- CD11240133
- Product name
- 5-Bromo-2-(chloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $897
- Updated
- 2021/12/16
Pyridine, 5-bromo-2-(chloromethyl)- (9CI) Chemical Properties,Usage,Production
Synthesis
88139-91-7
168823-76-5
Part B: 5-Bromo-2-hydroxymethylpyridine (500 mg, 2.7 mmol) was dissolved in dichloromethane (5 mL) and cooled in an ice bath to 0°C. Thionyl chloride (480 mg, 4.05 mmol) was added slowly dropwise, and after completion of the dropwise addition, the reaction mixture was transferred to room temperature and stirred for 3 hours. After completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution. The organic layer was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 5-bromo-2-chloromethylpyridine (510 mg, 92% yield).
References
[1] Journal of Porphyrins and Phthalocyanines, 2010, vol. 14, # 6, p. 469 - 480
[2] Patent: WO2007/84451, 2007, A1. Location in patent: Page/Page column 147
[3] Chemistry - A European Journal, 2011, vol. 17, # 38, p. 10670 - 10681
[4] Journal of Organic Chemistry, 2004, vol. 69, # 2, p. 250 - 262
[5] Patent: WO2006/76415, 2006, A2. Location in patent: Page/Page column 46
Pyridine, 5-bromo-2-(chloromethyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Pyridine, 5-bromo-2-(chloromethyl)- (9CI) Suppliers
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- Fax
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- info@chemstep.com
- Country
- Europe
- ProdList
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View Lastest Price from Pyridine, 5-bromo-2-(chloromethyl)- (9CI) manufacturers
- Product
- 5-Bromo-2-(chloromethyl)pyridine 168823-76-5
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-07
- Product
- Pyridine, 5-bromo-2-(chloromethyl)- (9CI) 168823-76-5
- Price
- US $0.37/g
- Min. Order
- 1g
- Purity
- 99%min cherry@coreychem.com
- Supply Ability
- 1kg/10kg
- Release date
- 2020-11-29