Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI)
- Product Name
- Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI)
- CAS No.
- 40428-87-3
- Chemical Name
- Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI)
- Synonyms
- 1-[3-(1-Methylethyl)phenyl]ethanone;Ethanone, 1-[3-(1-methylethyl)phenyl]-;Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI)
- CBNumber
- CB61064311
- Molecular Formula
- C11H14O
- Formula Weight
- 162.23
- MOL File
- 40428-87-3.mol
Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI) Property
- Boiling point:
- 84-90 °C(Press: 0.2 Torr)
- Density
- 0.948±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
N-Bromosuccinimide Price
- Product number
- 5442AB
- Product name
- 1-(3-Isopropylphenyl)ethanone
- Packaging
- 100mg
- Price
- $172
- Updated
- 2021/12/16
- Product number
- 5442AB
- Product name
- 1-(3-Isopropylphenyl)ethanone
- Packaging
- 250mg
- Price
- $244
- Updated
- 2021/12/16
- Product number
- AC0307
- Product name
- 1-(3-Isopropylphenyl)ethanone
- Packaging
- 1g
- Price
- $294
- Updated
- 2021/12/16
- Product number
- CHM0309552
- Product name
- 1-(3-ISOPROPYLPHENYL)ETHANONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.98
- Updated
- 2021/12/16
- Product number
- AC0307
- Product name
- 1-(3-Isopropylphenyl)ethanone
- Packaging
- 5g
- Price
- $701
- Updated
- 2021/12/16
Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI) Chemical Properties,Usage,Production
Synthesis
5433-01-2
78191-00-1
40428-87-3
A THF solution (250 mL) of 1-bromo-3-(propan-2-yl)benzene (5.0 g, 25.11 mmol, 1.00 eq.) was added to a 500 mL round-bottomed flask protected by an inert N2 atmosphere. The reaction system was cooled to -60 °C and n-butyllithium (20 mL, 2.00 eq.) was slowly added dropwise under stirring. After the dropwise addition, stirring was continued at -60 °C for 30 min. Subsequently, the reaction system was warmed to -30 °C and N-methoxy-N-methylacetamide (3.9 g, 37.82 mmol, 1.50 eq.) was added slowly dropwise under stirring. After completion of the dropwise addition, the reaction mixture was continued to be stirred in a liquid nitrogen bath at -30 °C for 3 hours. At the end of the reaction, the reaction was quenched by adding 20 mL of water. The reaction mixture was diluted with 200 mL of ethyl acetate, washed sequentially with 2 x 100 mL of brine, and the organic phase was dried over anhydrous Na2SO4 and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1:10) as eluent to give 2.7 g (66% yield) of the target product 1-(3-isopropylphenyl)ethanone as a colorless oil.
References
[1] Patent: WO2016/201426, 2016, A1. Location in patent: Paragraph 0243
[2] Patent: WO2013/78233, 2013, A1. Location in patent: Page/Page column 62
[3] Patent: WO2013/78240, 2013, A1. Location in patent: Page/Page column 57
[4] Patent: WO2017/214505, 2017, A1. Location in patent: Paragraph 000505; 000506
Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanone, 1-[3-(1-methylethyl)phenyl]- (9CI) Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58