5-CFDA, AM

Product Name: 5-CFDA, AM
CAS No.: 124412-00-6
Chemical Name: 5-CFDA, AM
Synonyms: CFDA-AM;5-CFDA, AM;5-Fam(Ac)2-AM;YDBUJZYYYBVSEF-UHFFFAOYSA-N;5-CFDA-AM, 90%, single isomer;CFDAAMCarboxyfluoresceindiacetateAMester;5-CARBOXYFLUORESCEIN DIACETATE, ACETOXYMETHYL ESTER;5-Carboxyfluorescein diacetate acetoxylmethyl ester;5-Carboxyfluorescein diacetate (acetyloxy)methyl ester;5-(AND-6)-CARBOXY SNARF(R)-1, ACETOXYMETHYL ESTER, ACETATE
CBNumber: CB6108173
Molecular Formula: C28H20O11
Formula Weight: 532.45
MOL File: 124412-00-6.mol

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5-CFDA, AM Property

Boiling point:: 737.0±60.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
form: Solid
color: White to off-white
Appearance: Solid Powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0012646
Product name: 5-CARBOXYFLUORESCEIN DIACETATE ACETOXYMETHYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $502.43
Updated: 2021/12/16

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5-CFDA, AM Chemical Properties,Usage,Production

Description

5-carboxyfluorescein diacetate acetoxymethyl ester is a cell-permeant fluorogenic esterase substrate. It can be converted by nonspecific esterases of living cells from a membrane-permeable, nonpolar, nonfluorescent substance to a polar product CF, indicating the integrity of the plasma membrane.

Uses

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1].

References

[1] Elena Gorokhova, et al. A comparison of TO-PRO-1 iodide and 5-CFDA-AM staining methods for assessing viability of planktonic algae with epifluorescence microscopy. J Microbiol Methods. 2012 Jun;89(3):216-21. DOI:10.1016/j.mimet.2012.03.005

5-CFDA, AM Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CFDA, AM Suppliers

China 11 Germany 2 United States 4 Global 17

3B Scientific Corporation

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Zymed Laboratories Inc.

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AnaSpec, Inc.

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International Laboratory Limited

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124412-00-6, 5-CFDA, AMRelated Search:

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5-CARBOXYFLUORESCEIN DIACETATE, ACETOXYMETHYL ESTER

5-CFDA, AM

5-(AND-6)-CARBOXY SNARF(R)-1, ACETOXYMETHYL ESTER, ACETATE

5-Carboxyfluorescein diacetate acetoxylmethyl ester

3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid (acetyloxy)methyl ester

5-CFDA-AM [5-carboxyfluorescein diacetate, acetoxymethyl ester]

YDBUJZYYYBVSEF-UHFFFAOYSA-N

5-CFDA-AM, 90%, single isomer

CFDA-AM

CFDAAMCarboxyfluoresceindiacetateAMester

5-Carboxyfluorescein diacetate (acetyloxy)methyl ester

Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, (acetyloxy)methyl ester

5-Fam(Ac)2-AM

124412-00-6

C28H20O11