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CBZ-L-PHENYLALANINAL

Product Name
CBZ-L-PHENYLALANINAL
CAS No.
59830-60-3
Chemical Name
CBZ-L-PHENYLALANINAL
Synonyms
CBZ-L-PHENYLALANINAL;(S)-Benzyl (1-oxo-3-phenylpropan-2-yl)carbamate;(S)-(-)-2-(Benzylcarbonylamino)-3-phenylpropanal;Carbamic acid, N-[(1S)-1-formyl-2-phenylethyl]-, phenylmethyl ester
CBNumber
CB61092987
Molecular Formula
C17H17NO3
Formula Weight
283.32
MOL File
59830-60-3.mol
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CBZ-L-PHENYLALANINAL Property

Melting point:
82 °C
Boiling point:
450.4±45.0 °C(Predicted)
Density 
1.168
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
11.17±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
5822AQ
Product name
Cbz-L-Phenylalaninal
Packaging
1g
Price
$345.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0003316
Product name
(S)-(-)-2-(BENZYLCARBONYLAMINO)-3-PHENYLPROPANAL
Purity
95.00%
Packaging
10MG
Price
$184.8
Updated
2021/12/16
AK Scientific
Product number
5822AQ
Product name
Cbz-L-Phenylalaninal
Packaging
5g
Price
$1011.2
Updated
2021/12/16
Chemenu
Product number
CM123391
Product name
benzyl(S)-(1-oxo-3-phenylpropan-2-yl)carbamate
Purity
95%
Packaging
1g
Price
$195
Updated
2021/12/16
Alichem
Product number
59830603
Product name
(S)-Benzyl(1-oxo-3-phenylpropan-2-yl)carbamate
Packaging
1g
Price
$216.32
Updated
2021/12/16
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CBZ-L-PHENYLALANINAL Chemical Properties,Usage,Production

Synthesis

114744-85-3

59830-60-3

The general procedure for the synthesis of N-Cbz-L-phenylalanine aldehyde from the compound (CAS:114744-85-3) was as follows: lithium aluminum hydride (0.95 mL of a 1.0 M THF solution, 0.95 mmol) was added to a solution containing benzyl [(S)-1-(methoxy-methyl-carbamoyl)-2-phenyl-ethyl]-carbamate (0.30 g of a 0.86 mmol) in a solution of THF (10 mL) and the reaction was carried out at room temperature. The resulting mixture was stirred at room temperature for 2 h. The reaction was subsequently terminated by dilution with the addition of ethyl acetate (200 mL) and washed with 1% aqueous hydrochloric acid (200 mL). The organic layer was dried with magnesium sulfate and concentrated under vacuum. The residue was repeatedly diluted with acetonitrile (2 x 200 mL) and concentrated under vacuum to give 0.24 g (yield as agreed) of benzyl ((S)-1-benzyl-2-oxo-ethyl)-carbamate as a colorless oil, which was used directly in the next reaction without further purification. Mass spectrometry analysis (ES+ LC/MS) showed m/e 284 (M+H), retention time (RT) = 4.75 min.

References

[1] Patent: US2008/139556, 2008, A1. Location in patent: Page/Page column 18; 46
[2] Journal of Organic Chemistry, 2016, vol. 81, # 4, p. 1416 - 1424
[3] Tetrahedron Letters, 2000, vol. 41, # 32, p. 6131 - 6135
[4] Tetrahedron, 1996, vol. 52, # 1, p. 305 - 318
[5] Tetrahedron Letters, 1998, vol. 39, # 11, p. 1341 - 1344

CBZ-L-PHENYLALANINAL Preparation Products And Raw materials

Raw materials

Preparation Products

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CBZ-L-PHENYLALANINAL Suppliers

China 22 Germany 1 India 1 United States 6 Global 30
Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
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sales@boylechem.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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+86-021-50935922
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+86-021-33847795
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Shijiazhuang Lickon PharmaTech Co., Ltd.
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Amadis Chemical Company Limited
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Wuxi AppTec
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Capot Chemical Co.,Ltd.
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59830-60-3, CBZ-L-PHENYLALANINALRelated Search:

N-Cbz-L-Phenylalanine Z-TYR(BZL)-OH Z-TYR-OH Z-TYR-ONP ZPCK Z-PHE-PRO-NH2 Z-PHE-ILE-OH Z-PHE-MET-OH Z-TYR-ALA-OH N-CARBOBENZOXY-L-TYROSINE DICYCLOHEXYLAMINE SALT Z-PHE-ALA-OH Z-PHE-GLY-OH Z-TYR-TYR-OH Z-PHE-PRO-OH Z-TYR(Z)-OH Z-PHE-MET-OME Z-PHE-TYR-OH Z-TYR-THR-OH

  • CBZ-L-PHENYLALANINAL
  • (S)-(-)-2-(Benzylcarbonylamino)-3-phenylpropanal
  • (S)-Benzyl (1-oxo-3-phenylpropan-2-yl)carbamate
  • Carbamic acid, N-[(1S)-1-formyl-2-phenylethyl]-, phenylmethyl ester
  • 59830-60-3