1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid

Product Name: 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS No.: 33972-97-3
Chemical Name: 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
Synonyms: 1-Methyl-2-oxo-1,2-dihydr...;1-Methyl-2-pyridone-4-carboxylic acid;1-methyl-2-oxopyridine-4-carboxylicaci;1-methyl-2-oxo-4-pyridinecarboxylic acid;1-methyl-2-oxopyridine-4-carboxylic acid;1-Methyl-2-oxo-1,2-dihydro-4-pyridine carboxylic a;1-methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid;4-Pyridinecarboxylic acid, 1,2-dihydro-1-Methyl-2-oxo-;1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid;1-methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid(SALTDATA: FREE)
CBNumber: CB61096213
Molecular Formula: C7H7NO3
Formula Weight: 153.14
MOL File: 33972-97-3.mol

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1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid Property

Melting point:: 260 °C
Boiling point:: 329.6±35.0 °C(Predicted)
Density: 1.381±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: solid
pka: 2.75±0.20(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C7H7NO3/c1-8-3-2-5(7(10)11)4-6(8)9/h2-4H,1H3,(H,10,11)
InChIKey: XUKWOJNDLIOXSC-UHFFFAOYSA-N
SMILES: C1(=O)N(C)C=CC(C(O)=O)=C1

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Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CBR00106
Product name: 1-Methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid
Purity: Aldrich
Packaging: 1g
Price: $356
Updated: 2025/07/31

TRC

Product number: B496025
Product name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylicAcid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-8N
Product name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 020304
Product name: 1-Methyl-2-oxo-1,2-dihydro-pyridine-4-carboxylic acid
Packaging: 500mg
Price: $182
Updated: 2021/12/16

AK Scientific

Product number: 4035AB
Product name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylicacid
Packaging: 10g
Price: $184
Updated: 2021/12/16

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1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid Chemical Properties,Usage,Production

Synthesis

20845-23-2

33972-97-3

GENERAL STEPS: Methyl 1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylate (1 g, 1.0 eq.) was dissolved in 25 mL of methanol and 5 mL of an aqueous solution of lithium hydroxide monohydrate (755 mg, 3.0 eq.) was added with stirring. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. An appropriate amount of water was added to the residue and the pH was adjusted to 1~3 with aqueous 3N hydrochloric acid. the resulting white solid product was collected by filtration, washed with water and dried to afford 1-methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid (540 mg, 60% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 13.56 (brs, 1H), 7.80 (d, J=1.2 Hz, 1H), 6.83 (d, J=1.6 Hz, 1H), 6.53 (d, J=6.8 Hz, 1H), 3.46 (s, 3H).

References

[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0229
[2] Patent: WO2007/67836, 2007, A2. Location in patent: Page/Page column 103

1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid Suppliers

China 69 India 3 United States 9 Global 81

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View Lastest Price from 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid 33972-97-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Career Henan Chemical Co

Product: 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid 33972-97-3
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-26

33972-97-3, 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acidRelated Search:

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1-Methyl-2-oxo-1,2-dihydr...

1-methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid(SALTDATA: FREE)

1-methyl-2-oxo-1,2-dihydro-4-pyridinecarboxylic acid

1-methyl-2-oxopyridine-4-carboxylic acid

1-Methyl-2-pyridone-4-carboxylic acid

1-methyl-2-oxo-4-pyridinecarboxylic acid

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1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid ISO 9001：2015 REACH

33972-97-3