2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID

Uses

Product Name: 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID
CAS No.: 191595-63-8
Chemical Name: 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID
Synonyms: 2-Hydroxy-6-(trifluromethyl)nicotinicacid;2-Hydroxy-6-triflroromethylnicotinic acid;2-Hydroxy-6-(trifluoromethyl)nicotinic acid;3-carboxyl-6-trifluoromethyl-1H-pyridin-2-one;2-Hydroxy-6-triflroroMethyl-3-pyridinecarboxylic acid;2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylicaci;2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylic acid;2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID ISO 9001：2015 REACH;1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 1,2-dihydro-2-oxo-6-(trifluoromethyl)-
CBNumber: CB61096460
Molecular Formula: C7H4F3NO3
Formula Weight: 207.11
MOL File: 191595-63-8.mol

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2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID Property

Melting point:: 165-167°C
Boiling point:: 328.9±42.0 °C(Predicted)
Density: 1.632±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 1.99±0.20(Predicted)
form: solid
Appearance: Light yellow to light brown Solid
InChI: 1S/C7H4F3NO3/c8-7(9,10)4-2-1-3(6(13)14)5(12)11-4/h1-2H,(H,11,12)(H,13,14)
InChIKey: JPOIZUVDMRHIIT-UHFFFAOYSA-N
SMILES: OC(=O)c1ccc(nc1O)C(F)(F)F

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Safety

WGK Germany: WGK 3
HS Code: 2933399990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: O990050
Product name: 2-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylicAcid
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: PC1877
Product name: 2-Hydroxy-6-(trifluoromethyl)nicotinicacid
Purity: 98%
Packaging: 1g
Price: $34
Updated: 2021/12/16

Matrix Scientific

Product number: 006874
Product name: 2-Hydroxy-6-(trifluoromethyl)nicotinic acid
Purity: 98%
Packaging: 1g
Price: $48
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H29-3-26
Product name: 2-Hydroxy-6-(trifluoromethyl)nicotinic acid
Purity: 98%
Packaging: 1g
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: X7046
Product name: 2-Hydroxy-6-(trifluoromethyl)nicotinicacid
Packaging: 250mg
Price: $83
Updated: 2021/12/16

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2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID Chemical Properties,Usage,Production

Uses

2-Hydroxy-6-trifluoromethylnicotinic acid is an important pharmaceutical intermediate, mainly used in the fields of medicine, food, and feed. It can also be used as an intermediate for bactericides.

Synthesis

Step 1, in a 250 ml three-necked flask, 10 g of 2-hydroxy-6-trifluoromethylnicotinonitrile, 16.2 g of phosphorus pentachloride and 40 g of phosphorus triclosan were added, heated to 100C, followed by HPLC, and the reaction was carried out for 6 h. The raw material was finished reacting, cooled, and was added to iced water, and was extracted by methylene chloride, and the organic phase was dried, filtered by extraction, and spun-dried, to give 9.2 g of solid 2-chloro-6-trifluoro Methylnicotinonitrile, purity is 93%. MS(EI)M+206(80.61)(M+2)+208(25.32).
Step 2, in a 50 ml single-necked flask, add 1 g of 2-chloro-6-trifluoromethylnicotinonitrile and 1.9 g of 40% sulfuric acid prepared in step 1, magnetically stirred, heated in an oil bath at 100 , and tracked by HPLC, reacted for 4 days, the raw material reaction was finished, cooled down, ice water was added, and extracted with ethyl acetate, and spun-dried to obtain 0.88 g of yellow solid 2-hydroxy-6-trifluoromethylnicotinic acid The purity was 95.6%.MS(EI)M+207(37.64).

2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID Suppliers

China 121 India 3 United Kingdom 4 United States 5 Global 133

Jinan Huicheng Pharm Tech Co., Ltd.

Tel: 1566-575-0038 13258035297
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Jinan Yaode Biotechnology Co., Ltd

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Shanghai Enong Biotechnology Co., LTD

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J & K SCIENTIFIC LTD.

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID 191595-63-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Dideu Industries Group Limited

Product: 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID 191595-63-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID 191595-63-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

191595-63-8, 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID Related Search:

Nicotinic acid N-Methylpropionamide TARTRONIC ACID Pyridine 2-Hydroxy-6-(trifluoromethyl)nicotinamide 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 2-Hydroxy-6-trifluoromethyl nicotinonitrile 2-Methylnicotinic acid 5-Hydroxynicotinic acid 5-(bromomethyl)-2-(trifluoromethyl)pyridine 2-HYDROXY-4-METHYL-6-(TRIFLUOROMETHYL)NICOTINIC ACID 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID RARECHEM AL BO 1059 2-Hydroxy-6-methylpyridine-3-carboxylic acid 6-(Trifluoromethyl)nicotinic acid

3-carboxyl-6-trifluoromethyl-1H-pyridin-2-one

2-Hydroxy-6-triflroromethylnicotinic acid

2-Hydroxy-6-triflroroMethyl-3-pyridinecarboxylic acid

2-Hydroxy-6-(trifluoromethyl)nicotinic acid

2-Hydroxy-6-(trifluoromethyl)pyridine-3-carboxylic acid, 3-Carboxy-2-hydroxy-6-(trifluoromethyl)pyridine

2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylic acid

2-Hydroxy-6-(trifluromethyl)nicotinicacid

3-Pyridinecarboxylic acid, 1,2-dihydro-2-oxo-6-(trifluoromethyl)-

2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylicaci

2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID ISO 9001：2015 REACH

2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid - [X22068]

1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid

191595-63-8

carboxylic acid

Carboxylic Acids

Pyridines

Carboxylic Acids