Sodium orthovanadate
- Product Name
- Sodium orthovanadate
- CAS No.
- 13721-39-6
- Chemical Name
- Sodium orthovanadate
- Synonyms
- SODIUM VANADATE;Sodium orthavanadium;Sodium Orthovanadate(Ⅴ);sodiumvanadate(v)(na3vo4);trisodium tetraoxovanadate;DECAVANDATE;trisodiumvanadate;SODIUM O-VANADATE;Is sodium vanadate;Pervanadate(100mM)
- CBNumber
- CB6111122
- Molecular Formula
- Na3VO4
- Formula Weight
- 183.91
- MOL File
- 13721-39-6.mol
Sodium orthovanadate Property
- Melting point:
- 850-866 °C(lit.)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- H2O: soluble
- form
- Solid
- color
- off-white
- Water Solubility
- soluble
- Exposure limits
- NIOSH: Ceiling 0.05 mg/m3
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 13721-39-6(CAS DataBase Reference)
- EPA Substance Registry System
- Sodium vanadium oxide (Na3VO4) (13721-39-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 567540
- Product name
- Sodium Orthovanadate - CAS 13721-39-6 - Calbiochem
- Purity
- A broad spectrum potent inhibitor of protein tyrosine phosphatases.
- Packaging
- 5G
- Price
- $71.1
- Updated
- 2024/03/01
- Product number
- 450243
- Product name
- Sodium orthovanadate
- Purity
- 99.98% trace metals basis
- Packaging
- 10g
- Price
- $75.1
- Updated
- 2024/03/01
- Product number
- 450243
- Product name
- Sodium orthovanadate
- Purity
- 99.98% trace metals basis
- Packaging
- 50g
- Price
- $201
- Updated
- 2024/03/01
- Product number
- 081104
- Product name
- Sodium orthovanadate, 99.9% (metals basis)
- Packaging
- 25g
- Price
- $89.1
- Updated
- 2024/03/01
- Product number
- 081104
- Product name
- Sodium orthovanadate, 99.9% (metals basis)
- Packaging
- 100g
- Price
- $298
- Updated
- 2024/03/01
Sodium orthovanadate Chemical Properties,Usage,Production
Chemical Properties
It forms colourless hexagonal columnar crystals that are soluble in water but insoluble in ethanol.
Uses
Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
Nanorods of vanadium oxide particles by glycothermal method.
Yttrium vanadate (YVO4) doped with colloidal europium.
Uses
Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.
Definition
ChEBI: Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a radiation protective agent, an apoptosis inducer and an antineoplastic agent. It contains a vanadate(3-).
Preparation
Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:
V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O
The salt features tetrahedral VO3-4 anion centers linked to octahedral Na+ cation sites.
Hazard
Poison by ingestion.
Biological Activity
Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Biochem/physiol Actions
Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS.
storage
Store at RT
Sodium orthovanadate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sodium orthovanadate manufacturers
- Product
- Sodium Orthovanadate 13721-39-6
- Price
- US $50.00/Kg/Drum
- Min. Order
- 25KG
- Purity
- 99%min
- Supply Ability
- 100tons/month
- Release date
- 2020-07-06
- Product
- Sodium orthovanadate 13721-39-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2021-11-11
- Product
- Sodium orthovanadate 13721-39-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-15