5-Amino-thiophene-2-carboxylic acid methyl ester
- Product Name
- 5-Amino-thiophene-2-carboxylic acid methyl ester
- CAS No.
- 14597-58-1
- Chemical Name
- 5-Amino-thiophene-2-carboxylic acid methyl ester
- Synonyms
- 5-aminothiophene-2-carboxylic methyl ester;5-Amino-thiophene-2-carboxylic acid methyl ester;2-Thiophenecarboxylicacid, 5-aMino-, Methyl ester
- CBNumber
- CB61113318
- Molecular Formula
- C6H7NO2S
- Formula Weight
- 157.19
- MOL File
- 14597-58-1.mol
5-Amino-thiophene-2-carboxylic acid methyl ester Property
- Melting point:
- 81 °C
- Boiling point:
- 304.8±22.0 °C(Predicted)
- Density
- 1.319±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.38±0.10(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C6H7NO2S/c1-9-6(8)4-2-3-5(7)10-4/h2-3H,7H2,1H3
- InChIKey
- NNQTUMGJWXJMIR-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)SC(N)=CC=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- M287475
- Product name
- Methyl5-Aminothiophene-2-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 7224AA
- Product name
- Methyl5-aminothiophene-2-carboxylate
- Packaging
- 250mg
- Price
- $111
- Updated
- 2021/12/16
- Product number
- P000253759
- Product name
- Methyl 5-aminothiophene-2-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $118
- Updated
- 2021/12/16
- Product number
- P000253759
- Product name
- Methyl 5-aminothiophene-2-carboxylate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- P000253759
- Product name
- Methyl 5-aminothiophene-2-carboxylate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $42
- Updated
- 2021/12/16
5-Amino-thiophene-2-carboxylic acid methyl ester Chemical Properties,Usage,Production
Synthesis
5832-01-9
14597-58-1
General procedure for the synthesis of methyl 5-amino-2-thiophenecarboxylate from methyl 5-nitro-2-thiophenecarboxylate: Methyl 5-nitro-2-thiophenecarboxylate (11.55 mmol) was dissolved in ethanol (20 mL), and 10% palladium carbon catalyst (1 g) was added. The reaction mixture was hydrogenated overnight with stirring under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was subsequently concentrated to afford the target product methyl 5-amino-2-thiophenecarboxylate (1.67 g, 92% yield). The product was detected by LCMS (ESI) and showed a molecular ion peak of 157 [M+H]+.
References
[1] Patent: WO2006/65788, 2006, A2. Location in patent: Page/Page column 10
[2] Patent: US2007/43045, 2007, A1. Location in patent: Page/Page column 59
[3] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 10, p. 1379 - 1382
[4] Patent: WO2004/108683, 2004, A1. Location in patent: Page 564-565
[5] Patent: WO2004/18480, 2004, A1. Location in patent: Page 156
5-Amino-thiophene-2-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Amino-thiophene-2-carboxylic acid methyl ester manufacturers
- Product
- 5-Amino-thiophene-2-carboxylic acid methyl ester 14597-58-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- 1ton
- Release date
- 2019-12-18