2-Maleimido acetic acid

Product Name: 2-Maleimido acetic acid
CAS No.: 25021-08-3
Chemical Name: 2-Maleimido acetic acid
Synonyms: 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid;NSC 266055;N-Maleoylglycine;N-MaleiMidoglycine;N,N-maleoyl-glycine;MALEIMIDOACETIC ACID;2-maleimide acetic acid;2-MALEIMIDO ACETIC ACID;N-(CarboxyMethyl)MaleiMide;2-MALEIMIDO ACETIC ACID 97%
CBNumber: CB61118111
Molecular Formula: C6H5NO4
Formula Weight: 155.11
MOL File: 25021-08-3.mol

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2-Maleimido acetic acid Property

Melting point:: 114 °C(Solv: chloroform (67-66-3))
Boiling point:: 376.7±25.0 °C(Predicted)
Density: 1.578±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in DMSO, Methanol
form: powder to crystal
pka: 3.31±0.10(Predicted)
color: White to Almost white
InChI: InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11)
InChIKey: GBKPNGVKZQBPCZ-UHFFFAOYSA-N
SMILES: N1(CC(O)=O)C(=O)C=CC1=O

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Safety

HS Code: 2925.19.4200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3143
Product name: 2-Maleimidoacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 50mg
Price: $65
Updated: 2024/03/01

TCI Chemical

Product number: M3143
Product name: 2-Maleimidoacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 250mg
Price: $191
Updated: 2024/03/01

TRC

Product number: M124990
Product name: MaleimidoaceticAcid
Packaging: 250mg
Price: $135
Updated: 2021/12/16

Matrix Scientific

Product number: 119970
Product name: 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
Purity: 95+%
Packaging: 1g
Price: $810
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0155638
Product name: 2-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)ACETIC ACID
Purity: 95.00%
Packaging: 1G
Price: $925.31
Updated: 2021/12/16

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2-Maleimido acetic acid Chemical Properties,Usage,Production

Chemical Properties

White to Almost white powder to crystal or Pale Yellow Solid.

Uses

Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.

Application

2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.

References

[1] Gabano E, et al. Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. Inorganica Chimica Acta, 2019; 488: 195-200.

2-Maleimido acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Maleimido acetic acid Suppliers

Americas 1 Canada 1 China 111 Europe 1 India 3 Japan 1 United Kingdom 1 United States 10 Global 129

Suzhouhongxiong

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Nanjing Vital Chemical Co., Ltd.

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View Lastest Price from 2-Maleimido acetic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Maleimido acetic acid 25021-08-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Maleimido acetic acid 25021-08-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: 2-Maleimido acetic acid 25021-08-3
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

25021-08-3, 2-Maleimido acetic acidRelated Search:

DISUCCINIMIDYL SUBERATE Suberate Bis(sulfosuccinimidyl) Sodium Salt N-Succinimidyl maleimidoacetate 3-(BENZOPHENONE-4-CARBOXAMIDO)-2-MALEIMIDOPROPANOIC ACID 2-Maleimido acetic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methanesulfonylbutanoic acid 2-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-phenylpropanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylbutanoic acid DACM 3-MALEIMIDO-4-METHYL-6,7-METHYLENEDIOXYCOUMARIN RARECHEM AL CD 0491 4-carbamoyl-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylpentanoic acid 9-ACETOXY-2-(4-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-3-OXO-3-H-NAPHTHO[2,1-B]PYRAN 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-(1H-imidazol-4-yl)propanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylpentanoic acid methyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate

2-MALEIMIDOACETIC ACID DIHYDRATE

N-Maleoylglycine

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-acetic Acid

N-(CarboxyMethyl)MaleiMide

N-MaleiMidoglycine

NSC 266055

2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid

MAA 2-Maleimido acetic acid

2-MALEIMIDO ACETIC ACID 97%

2-(2,5-dioxopyrrol-1-yl)acetic acid

2-Maleimido acetic acid(MAA)

1H-Pyrrole-1-acetic acid, 2,5-dihydro-2,5-dioxo-

2-maleimide acetic acid

2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-acetic acid

MALEIMIDOACETIC ACID

2-MALEIMIDO ACETIC ACID

N,N-maleoyl-glycine

25021-08-3

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