1-O-Hexyl-2,3,5-trimethylhydroquinone

Product Name: 1-O-Hexyl-2,3,5-trimethylhydroquinone
CAS No.: 148081-72-5
Chemical Name: 1-O-Hexyl-2,3,5-trimethylhydroquinone
Synonyms: CS-2408;HX-1171;4-hexoxy-2;1-O-Hexyl-2;HX-1171(HTHQ);HTHQ(HX-1171);6-trimethylphenol;HTHQ, 10 mM in DMSO;5-trimethylhydroquinone;HEXYLOXY TRIMETHYLPHENOL
CBNumber: CB61175507
Molecular Formula: C15H24O2
Formula Weight: 236.35
MOL File: 148081-72-5.mol

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1-O-Hexyl-2,3,5-trimethylhydroquinone Property

Melting point:: 72.5-73°C
Boiling point:: 357.8±37.0 °C(Predicted)
Density: 0.971±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform：soluble
pka: 11.22±0.30(Predicted)
form: powder to crystal
color: White to Light yellow to Dark green
LogP: 5.255 (est)

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Safety

HS Code: 2909.50.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: H1741
Product name: 4-(Hexyloxy)-2,3,6-trimethylphenol
Packaging: 50MG
Price: $43
Updated: 2025/07/31

TCI Chemical

Product number: H1741
Product name: 4-(Hexyloxy)-2,3,6-trimethylphenol
Packaging: 250MG
Price: $129
Updated: 2025/07/31

Cayman Chemical

Product number: 22652
Product name: HX 1171
Purity: ≥98%
Packaging: 50mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 22652
Product name: HX 1171
Purity: ≥98%
Packaging: 100mg
Price: $135
Updated: 2024/03/01

TRC

Product number: H325000
Product name: 1-O-Hexyl-2,3,5-trimethylhydroquinone
Packaging: 500mg
Price: $480
Updated: 2021/12/16

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1-O-Hexyl-2,3,5-trimethylhydroquinone Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Low Melting Solid

Uses

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals[1][2].

in vivo

HTHQ (50-200 mg/kg; oral administration; for 4 weeks; specific pathogen-free male Sprague Dawley rats) treatment significantly improves liver weight and serum chemistry level. HTHQ reduces hydroxyproline and malondialdehyde level in the liver. HTHQ treatment also reduces fibrotic septa. HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue^[2].

Animal Model:	48 specific pathogen-free male Sprague Dawley (SD) rats (6-week-old ) with dimethylnitrosamine (DMN) ^[2]
Dosage:	50 mg/kg, 100 mg/kg, 200 mg/kg
Administration:	Oral administration; for 4 weeks
Result:	Improved against DMN-induced liver fibrosis in male SD rats.

References

[1] Park HJ, et al. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells. Molecules. 2019 Mar 1;24(5). pii: E867. DOI:10.3390/molecules24050867
[2] Jung YR et al. Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats. Toxicol Res. 2010 Sep;26(3):193-201. DOI:10.5487/TR.2010.26.3.193

1-O-Hexyl-2,3,5-trimethylhydroquinone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-Hexyl-2,3,5-trimethylhydroquinone Suppliers

Americas 1 Canada 1 China 58 Europe 1 India 3 Japan 1 South Korea 1 United States 11 Global 77

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View Lastest Price from 1-O-Hexyl-2,3,5-trimethylhydroquinone manufacturers

Career Henan Chemical Co

Product: 1-O-Hexyl-2,3,5-trimethylhydroquinone 148081-72-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

148081-72-5, 1-O-Hexyl-2,3,5-trimethylhydroquinoneRelated Search:

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4-Hexyloxy-2,3,6-triMethylphenol

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1-O-Hexyl-2

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4-HEXOXY-2;3;6-TRIMETHYLPHENOL;1-O-HEXYL-2;3;5-TRIMETHYLHYDROQUINONE

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6-trimethylphenol

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Phenol, 4-(hexyloxy)-2,3,6-trimethyl-

HEXYLOXY TRIMETHYLPHENOL

HX-1171(HTHQ)

HTHQ(HX-1171)

BTT 105,BTT105,inhibit,BTT-105,HTHQ,HX1171,Reactive Oxygen Species,Inhibitor,HX-1171

HTHQ, 10 mM in DMSO

HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone) ，S5314

148081-72-5

Detergents

Mutagenesis Research Chemicals