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1-O-Hexyl-2,3,5-trimethylhydroquinone

Product Name
1-O-Hexyl-2,3,5-trimethylhydroquinone
CAS No.
148081-72-5
Chemical Name
1-O-Hexyl-2,3,5-trimethylhydroquinone
Synonyms
CS-2408;HX-1171;4-hexoxy-2;1-O-Hexyl-2;HX-1171(HTHQ);HTHQ(HX-1171);6-trimethylphenol;HTHQ, 10 mM in DMSO;5-trimethylhydroquinone;HEXYLOXY TRIMETHYLPHENOL
CBNumber
CB61175507
Molecular Formula
C15H24O2
Formula Weight
236.35
MOL File
148081-72-5.mol
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1-O-Hexyl-2,3,5-trimethylhydroquinone Property

Melting point:
72.5-73°C
Boiling point:
357.8±37.0 °C(Predicted)
Density 
0.971±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform：soluble
pka
11.22±0.30(Predicted)
form 
powder to crystal
color 
White to Light yellow to Dark green
LogP
5.255 (est)
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Safety

HS Code 
2909.50.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H1741
Product name
4-(Hexyloxy)-2,3,6-trimethylphenol
Packaging
50MG
Price
$43
Updated
2025/07/31
TCI Chemical
Product number
H1741
Product name
4-(Hexyloxy)-2,3,6-trimethylphenol
Packaging
250MG
Price
$129
Updated
2025/07/31
Cayman Chemical
Product number
22652
Product name
HX 1171
Purity
≥98%
Packaging
50mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
22652
Product name
HX 1171
Purity
≥98%
Packaging
100mg
Price
$135
Updated
2024/03/01
TRC
Product number
H325000
Product name
1-O-Hexyl-2,3,5-trimethylhydroquinone
Packaging
500mg
Price
$480
Updated
2021/12/16
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1-O-Hexyl-2,3,5-trimethylhydroquinone Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Low Melting Solid

Uses

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals[1][2].

in vivo

HTHQ (50-200 mg/kg; oral administration; for 4 weeks; specific pathogen-free male Sprague Dawley rats) treatment significantly improves liver weight and serum chemistry level. HTHQ reduces hydroxyproline and malondialdehyde level in the liver. HTHQ treatment also reduces fibrotic septa. HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue[2].

Animal Model:48 specific pathogen-free male Sprague Dawley (SD) rats (6-week-old ) with dimethylnitrosamine (DMN) [2]
Dosage:50 mg/kg, 100 mg/kg, 200 mg/kg
Administration:Oral administration; for 4 weeks
Result:Improved against DMN-induced liver fibrosis in male SD rats.

References

[1] Park HJ, et al. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells. Molecules. 2019 Mar 1;24(5). pii: E867. DOI:10.3390/molecules24050867
[2] Jung YR et al. Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats. Toxicol Res. 2010 Sep;26(3):193-201. DOI:10.5487/TR.2010.26.3.193

1-O-Hexyl-2,3,5-trimethylhydroquinone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-Hexyl-2,3,5-trimethylhydroquinone Suppliers

Americas 1 Canada 1 China 58 Europe 1 India 3 Japan 1 South Korea 1 United States 11 Global 77
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 1-O-Hexyl-2,3,5-trimethylhydroquinone manufacturers

Career Henan Chemical Co
Product
1-O-Hexyl-2,3,5-trimethylhydroquinone 148081-72-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

148081-72-5, 1-O-Hexyl-2,3,5-trimethylhydroquinoneRelated Search:

1,4-Pentadien-3-ol 1-O-Hexyl-2,3,5-trimethylhydroquinone

  • 4-(Hexyloxy)-2,3,6-triMethyl-phenol
  • 4-Hexyloxy-2,3,6-triMethylphenol
  • HX-1171
  • 1-O-Hexyl-2
  • 4-hexoxy-2
  • 4-HEXOXY-2;3;6-TRIMETHYLPHENOL;1-O-HEXYL-2;3;5-TRIMETHYLHYDROQUINONE
  • 5-trimethylhydroquinone
  • 6-trimethylphenol
  • 4-hexoxy-2,3,6-trimethylphenol
  • CS-2408
  • HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)
  • Phenol, 4-(hexyloxy)-2,3,6-trimethyl-
  • HEXYLOXY TRIMETHYLPHENOL
  • HX-1171(HTHQ)
  • HTHQ(HX-1171)
  • BTT 105,BTT105,inhibit,BTT-105,HTHQ,HX1171,Reactive Oxygen Species,Inhibitor,HX-1171
  • HTHQ, 10 mM in DMSO
  • HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone) ，S5314
  • 148081-72-5
  • Detergents
  • Mutagenesis Research Chemicals