Solifenacin Hydrochloride
- Product Name
- Solifenacin Hydrochloride
- CAS No.
- 180468-39-7
- Chemical Name
- Solifenacin Hydrochloride
- Synonyms
- Solifenacin HCl;YM905 hydrochloride;YM 905 hydrochloride;YM-905 hydrochloride;Vesicare hydrochloride;Solifenacin Succinate 3;Solifenacin Hydrochloride;VESICARE HYDROCHLORIDE;YM905 HYDROCHLORIDE;YM 905 HYDROCHLORIDE;YM-905 HYDROCHLORIDE;(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochlorid;(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride
- CBNumber
- CB61176791
- Molecular Formula
- C23H27ClN2O2
- Formula Weight
- 398.93
- MOL File
- 180468-39-7.mol
Solifenacin Hydrochloride Property
- Melting point:
- 120-122°C
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- S676700
- Product name
- SolifenacinHydrochloride
- Packaging
- 5mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 289163
- Product name
- Solifenacin hydrochloride
- Packaging
- 5mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- CS-2661
- Product name
- Solifenacin(hydrochloride)
- Purity
- 99.29%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- B3415
- Product name
- Solifenacinhydrochloride
- Packaging
- 100mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- CS-2661
- Product name
- Solifenacin(hydrochloride)
- Purity
- 99.29%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
Solifenacin Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Muscarinic M3 receptor antagoinst used in treatment of urinary incontinence.
Uses
Solifenacin Hydrochloride can be used as muscarinic M3 receptor antagoinst and used in treatment of urinary incontinence
in vivo
Solifenacin hydrochloride (YM905 hydrochloride) reduces bladder responses by 40% at a dose of 210 nmol/kg (0.1 mg/kg) and abolishes them at 2100 nmol/kg (1 mg/kg). In contrast, its inhibitory effects on salivary and cardiac responses are only slight at 630 nmol/kg (0.3 mg/kg), and reach 66% and 49%, respectively, at 2100 nmol/kg (1 mg/kg). At doses of 63 and 210 nmol/kg (0.03 and 0.1 mg/kg), Solifenacin hydrochloride slightly increases saliva secretion[1]. Solifenacin hydrochloride (0.01 to 0.3 mg/kg i.v.) dose-dependently increases bladder capacity and voided volume at doses of 0.03 mg/kg i.v. or more, but does not affect residual volume or micturition pressure at any dose tested[2].
IC 50
mAChR2; mAChR1; mAChR3