KAHWEOL
- Product Name
- KAHWEOL
- CAS No.
- 6894-43-5
- Chemical Name
- KAHWEOL
- Synonyms
- KAHWEOL;Kahweol-RM;KAHWEOL USP/EP/BP;Kahweol, 10 mM in DMSO;Kahweol DISCONTINUED, unstable;Kahweol, Diterpene molecule in coffee beans;(3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;[3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
- CBNumber
- CB6117982
- Molecular Formula
- C20H26O3
- Formula Weight
- 314.42
- MOL File
- 6894-43-5.mol
KAHWEOL Property
- Melting point:
- 88-90℃
- Boiling point:
- 476.6±45.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM) - pka
- 14.43±0.40(Predicted)
- form
- White to off-white solid.
- color
- Off-white to light yellow
- LogP
- 3.380 (est)
N-Bromosuccinimide Price
- Product number
- PHL82293
- Product name
- Kahweol
- Purity
- phyproof<SUP>®</SUP> Reference Substance
- Packaging
- 20 mg
- Price
- $271
- Updated
- 2025/07/31
- Product number
- 14015
- Product name
- Kahweol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 14015
- Product name
- Kahweol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $135
- Updated
- 2024/03/01
- Product number
- 14015
- Product name
- Kahweol
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $315
- Updated
- 2024/03/01
- Product number
- orb594400
- Product name
- Kahweol
- Packaging
- 20mg
- Price
- $391
- Updated
- 2021/12/16
KAHWEOL Chemical Properties,Usage,Production
Uses
Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.
Definition
ChEBI: Kahweol is a diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. It has a role as an angiogenesis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a diterpenoid, a member of furans, an organic heteropentacyclic compound, a tertiary alcohol and a primary alcohol.
KAHWEOL Preparation Products And Raw materials
Raw materials
Preparation Products
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