Zetidoline

Product Name: Zetidoline
CAS No.: 51940-78-4
Chemical Name: Zetidoline
Synonyms: MDL-308;Zetidoline;1-(3-Chlorophenyl)-3-[2-(3,3-dimethylazetidin-1-yl)ethyl]-2-imidazolidinone;2-Imidazolidinone, 1-(3-chlorophenyl)-3-[2-(3,3-dimethyl-1-azetidinyl)ethyl]-
CBNumber: CB61180095
Molecular Formula: C16H22ClN3O
Formula Weight: 307.823
MOL File: 51940-78-4.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0012818
Product name: ZETIDOLINE
Purity: 95.00%
Packaging: 5MG
Price: $502.34
Updated: 2021/12/16

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Zetidoline Chemical Properties,Usage,Production

Originator

MDL 308 ,Dow Chemical

Manufacturing Process

A solution of 5.0 g of 1-(m-chlorophenyl)-2-imidazolidinone in 30 ml of dimethylformamide is added at room temperature to a mixture of 1.5 g of 50% NaH (mineral oil emulsion) in 30 ml of dimethylformamide. The reaction mixture is stirred for 1 h at room temperature and then 4.5 g of 3,3-dimethyl- 1-(2-chloroethyl)azetidine are added. The mixture is stirred again at room temperature for 2 h and then it is heated for 5 h at 80°-85°C. The salts are filtered off and the solvent is removed under vacuum. The residue is taken up with 8 ml of 18% HCl and 16 ml of water and extracted with diethyl ether. The water solution is alkalinized by addition of 15% sodium carbonate and then extracted with diethyl ether. By evaporation of the organic layer a residue is obtained that is triturated in light petroleum. Yield of 1-(m- chlorophenyl)-3-[2-(3,3-dimethylazetidin-1-y1)ethyl]-2-imidazolidinone 7.25 g, melting point 84°-85°C (after recrystallization from hexane).

Therapeutic Function

Antipsychotic, Neuroleptic

Zetidoline Preparation Products And Raw materials

Raw materials

Preparation Products

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Zetidoline Suppliers

China 3 United States 1 Global 4

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1922
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 17691182729 13992773979
Email: 1049@dideu.com
Country: China
ProdList: 8012
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

51940-78-4, ZetidolineRelated Search:

1-(2-AMINOETHYL)-2-IMIDAZOLIDONE 3,3-DIMETHYLAZETIDINE HYDROCHLORIDE 3-METHYLAZETIDINE HYDROCHLORIDE Imidoline 1,3-Dimethyl-2-imidazolidinone Zetidoline

Zetidoline

1-(3-Chlorophenyl)-3-[2-(3,3-dimethylazetidin-1-yl)ethyl]-2-imidazolidinone

MDL-308

2-Imidazolidinone, 1-(3-chlorophenyl)-3-[2-(3,3-dimethyl-1-azetidinyl)ethyl]-

51940-78-4