(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid

Product Name: (2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid
CAS No.: 124505-87-9
Chemical Name: (2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid
Synonyms: Pentosidine;Pentosidine. TFA salt;Gefitinib Impurity 109;PENTOSIDINE 2,2,2-TRIFLUOROACETATE;4H-Imidazo[4,5-b]pyridine-4-hexanoic acid, α-amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-, (αS)-;4H-Imidazo(4,5-B)pyridine-4-hexanoic acid, alpha-amino-2-((4-amino-4-carboxybutyl)amino)-, (S-(R*,R*))-;4H-Imidazo(4,5-B)pyridine-4-hexanoic acid, alpha-amino-2-(((4S)-4-amino-4-carboxybutyl)amino)-, (alphas)-;(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid;2-((S)-4-ACETAMIDO-4-CARBOXYBUTYLAMINO)-4-((S)-5-ACETAMIDO-5-CARBOXYPENTYL)-3H-IMIDAZO[4,5-B]PYRIDIN-4-IUM 2,2,2-TRIFLUOROACETATE
CBNumber: CB61236187
Molecular Formula: C17H26N6O4
Formula Weight: 378.43
MOL File: 124505-87-9.mol

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(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid Property

Boiling point:: 655.6±65.0 °C(Predicted)
Density: 1.47±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 21.4 mg/ml; DMSO: 22.4 mg/ml; Ethanol: 31.3 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
pka: 2.50±0.24(Predicted)
Stability:: Hygroscopic

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Safety

HS Code: 2922498590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010254
Product name: Pentosidine
Purity: ≥98%
Packaging: 1mg
Price: $236
Updated: 2023/06/20

Cayman Chemical

Product number: 10010254
Product name: Pentosidine
Purity: ≥98%
Packaging: 5mg
Price: $1060
Updated: 2023/06/20

Cayman Chemical

Product number: 10010254
Product name: Pentosidine
Purity: ≥98%
Packaging: 10mg
Price: $1884
Updated: 2023/06/20

AK Scientific

Product number: 8461CA
Product name: Pentosidine
Packaging: 10mg
Price: $2238
Updated: 2021/12/16

AK Scientific

Product number: 8461CA
Product name: Pentosidine
Packaging: 5mg
Price: $1302
Updated: 2021/12/16

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(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid Chemical Properties,Usage,Production

Description

Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling. Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of this AGE is catabolized before excretion.

Uses

A biochemical marker of bone turnover for management of metabolic bone diseases.

Definition

ChEBI: An imidazopyridine having norleucine and ornithine residues attached via their side-chains at the 4- and 2-positions respectively.

(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid Suppliers

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124505-87-9, (2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acidRelated Search:

(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE

Pentosidine. TFA salt

PENTOSIDINE 2,2,2-TRIFLUOROACETATE

4H-Imidazo(4,5-B)pyridine-4-hexanoic acid, alpha-amino-2-(((4S)-4-amino-4-carboxybutyl)amino)-, (alphas)-

4H-Imidazo(4,5-B)pyridine-4-hexanoic acid, alpha-amino-2-((4-amino-4-carboxybutyl)amino)-, (S-(R*,R*))-

2-((S)-4-ACETAMIDO-4-CARBOXYBUTYLAMINO)-4-((S)-5-ACETAMIDO-5-CARBOXYPENTYL)-3H-IMIDAZO[4,5-B]PYRIDIN-4-IUM 2,2,2-TRIFLUOROACETATE

(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid

Pentosidine

4H-Imidazo[4,5-b]pyridine-4-hexanoic acid, α-amino-2-[[(4S)-4-amino-4-carboxybutyl]amino]-, (αS)-

Gefitinib Impurity 109

124505-87-9

1049739-88-9

C1613CH24D2N6O4

Amines

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Pharmaceuticals