ChemicalBook > CAS DataBase List > N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
- Product Name
- N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
- CAS No.
- 53774-63-3
- Chemical Name
- N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
- Synonyms
- L NIL,LNIL;H-LYS(ACETIMIDOYL)-OH;H-LYS(1-IMINOETHYL)-OH;LYSINE(ACETIMIDOYL)-OH;Ne-Acetimidoyl-L-lysine;N-ε-Acetimidoyl-L-lysine;N-(5-Amino-5-carboxypentyl;L-Lysine, N6-(1-iMinoethyl)-;N-EPSILON-ACETIMIDOYL-L-LYSINE;N-EPSILON-ACETIMIDOYL-L-LYSIN-EPSILON
- CBNumber
- CB1325601
- Molecular Formula
- C8H17N3O2
- Formula Weight
- 187.24
- MOL File
- 53774-63-3.mol
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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Property
- Boiling point:
- 335.2±52.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- Water: 50 mg/mL (267.04 mM); DMSO: < 1 mg/mL (insoluble or slightly soluble)
- pka
- 2.52±0.24(Predicted)
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-7870
- Product name
- L-NIL
- Purity
- 99.96%
- Packaging
- 50mg
- Price
- $108
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7870
- Product name
- L-NIL
- Purity
- 99.96%
- Packaging
- 100mg
- Price
- $192
- Updated
- 2021/12/16
Chem-Impex
- Product number
- 06128
- Product name
- Nε-Acetimidoyl-L-lysine,99%
- Purity
- 99%
- Packaging
- 5G
- Price
- $495.04
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0004800
- Product name
- H-LYS(1-IMINOETHYL)-OH
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.89
- Updated
- 2021/12/16
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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Chemical Properties,Usage,Production
Biological Activity
L-NIL is an inhibitor of inducible nitric oxide synthase (iNOS) with an IC50 value of 3.3 μM for miNOS.
in vitro
L-NIL produces a concentration-dependent inhibition of both the mouse inducible NOS (miNOS) and the rat brain constitutive NOS (rcNOS) and is considerably more potent for miNOS. The IC 50 values for L-NIL with miNOS and rcNOS are 3.3 and 92 pM, respectively, indicating that it is 28-fold more selective for miNOS. In addition, L-NIL has approximately 6-fold greater potency for miNOS than either L -NMA or L-NNA.
target
IC50: 3.3 μM (mouse inducible NO synthase), 92 μM (rat brain constitutive NO synthase)
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Suppliers
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53774-63-3, N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINERelated Search:
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE
(2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid