ChemicalBook > CAS DataBase List > N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE

N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE

Product Name
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
CAS No.
53774-63-3
Chemical Name
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
Synonyms
L NIL,LNIL;H-LYS(ACETIMIDOYL)-OH;H-LYS(1-IMINOETHYL)-OH;LYSINE(ACETIMIDOYL)-OH;Ne-Acetimidoyl-L-lysine;N-ε-Acetimidoyl-L-lysine;N-(5-Amino-5-carboxypentyl;L-Lysine, N6-(1-iMinoethyl)-;N-EPSILON-ACETIMIDOYL-L-LYSINE;N-EPSILON-ACETIMIDOYL-L-LYSIN-EPSILON
CBNumber
CB1325601
Molecular Formula
C8H17N3O2
Formula Weight
187.24
MOL File
53774-63-3.mol
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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Property

Boiling point:
335.2±52.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
Water: 50 mg/mL (267.04 mM); DMSO: < 1 mg/mL (insoluble or slightly soluble)
form 
Solid
pka
2.52±0.24(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7870
Product name
L-NIL
Purity
99.96%
Packaging
50mg
Price
$108
Updated
2021/12/16
ChemScene
Product number
CS-7870
Product name
L-NIL
Purity
99.96%
Packaging
100mg
Price
$192
Updated
2021/12/16
Chem-Impex
Product number
06128
Product name
Nε-Acetimidoyl-L-lysine,99%
Purity
99%
Packaging
5G
Price
$495.04
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004800
Product name
H-LYS(1-IMINOETHYL)-OH
Purity
95.00%
Packaging
5MG
Price
$505.89
Updated
2021/12/16
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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Chemical Properties,Usage,Production

Biological Activity

L-NIL is an inhibitor of inducible nitric oxide synthase (iNOS) with an IC50 value of 3.3 μM for miNOS.

in vitro

L-NIL produces a concentration-dependent inhibition of both the mouse inducible NOS (miNOS) and the rat brain constitutive NOS (rcNOS) and is considerably more potent for miNOS. The IC 50 values for L-NIL with miNOS and rcNOS are 3.3 and 92 pM, respectively, indicating that it is 28-fold more selective for miNOS. In addition, L-NIL has approximately 6-fold greater potency for miNOS than either L -NMA or L-NNA.

target

IC50: 3.3 μM (mouse inducible NO synthase), 92 μM (rat brain constitutive NO synthase)

N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE Suppliers

China 22 India 1 Japan 1 United States 7 Global 31
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53774-63-3, N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINERelated Search:

N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE L-N6-(1-IMINOETHYL)LYSINE DIHYDROCHLORIDE (2S)-2-amino-6-[8-[[(4S)-4-amino-4-carboxy-butyl]amino]-2,7,9-triazabicyclo[4.3.0]nona-3,5,7,9-tetraen-2-yl]hexanoic acid

  • N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
  • N-EPSILON-ACETIMIDOYL-L-LYSINE
  • N-EPSILON-ACETIMIDOYL-L-LYSIN-EPSILON
  • H-LYS(1-IMINOETHYL)-OH
  • H-LYS(ACETIMIDOYL)-OH
  • LYSINE(ACETIMIDOYL)-OH
  • N-(5-Amino-5-carboxypentyl
  • Ne-Acetimidoyl-L-lysine
  • L-Lysine, N6-(1-iMinoethyl)-
  • N-(5-AMino-5-carboxypentyl)-acetaMidine, H-Lys(1-iMinoethyl)-OH, L-NIL
  • N-ε-Acetimidoyl-L-lysine
  • L NIL,LNIL
  • 53774-63-3
  • C8H17N3O2