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AMIPROFOS METHYL

Product Name
AMIPROFOS METHYL
CAS No.
36001-88-4
Chemical Name
AMIPROFOS METHYL
Synonyms
ntn80;ntn6867;bayntn80;NTN-2925;Tokunol-M;bayntn6867;amiprophosmethyl;AMIPROFOS METHYL;Amiprofosmethylbiochemika;O-METHYL O-(2-NITRO-P-TOLYL) N-ISOPROPYL-PHOSPHORAMIDOTHIONATE
CBNumber
CB6124212
Molecular Formula
C11H17N2O4PS
Formula Weight
304.3
MOL File
36001-88-4.mol
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AMIPROFOS METHYL Property

Melting point:
~65 °C
Boiling point:
146.6°C
Density 
1.275±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-0.73±0.70(Predicted)
form 
Solid
color 
White to Off-White
BRN 
2000833
EPA Substance Registry System
Amiprofos-methyl (36001-88-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
TB5100000
Toxicity
LD50 orl-rat: 309 mg/kg 85AREA 2,212,77
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
03992
Product name
Amiprofos methyl
Purity
PESTANAL , analytical standard
Packaging
50mg
Price
$237
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
10mg
Price
$60
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
50mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
100mg
Price
$185
Updated
2024/03/01
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AMIPROFOS METHYL Chemical Properties,Usage,Production

Description

Amiprofos-methyl (APM) is a phosphoric amide herbicide. It reversibly decreases H. vulgare root and shoot length and inhibits in vitro polymerization of Rosa tubulin induced by paclitaxel in a dose-dependent manner. APM completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM. The antitubulin effects of APM are specific to plants as it has no effect on bovine brain tubulin polymerization at concentrations up to 100 μM. APM inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM. APM inhibits the growth of P. falciparum (IC50 = 3.5 μM) and completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM.

Uses

Amiprofos-methyl is useful in herbicide compositions.

Biochem/physiol Actions

Herbicide that prevents microtubule polymerization in plant cells, but not animal cells. Crop plants resistant to amiprofos-methyl and several other herbicides have been developed by insertion of a xenobiotic-detoxifying human gene CYP2B6.

Safety Profile

A poison by ingestion. Lowtoxicity by skin contact. When heated to decomposition itemits toxic vapors of NOx, SOx, and POx.

AMIPROFOS METHYL Preparation Products And Raw materials

Raw materials

Preparation Products

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AMIPROFOS METHYL Suppliers

Beijing VSciChem Technology Co., Ltd.
Tel
13811761079
Email
vscichem@163.com
Country
China
ProdList
245
Advantage
64
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4515
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20512
Advantage
60
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4880
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
9939
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-62971590 18548936886
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
6912
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55827
Advantage
58

36001-88-4, AMIPROFOS METHYLRelated Search:


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  • NTN-2925
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  • Phosphoramidothioic acid, N-(1-methylethyl)-, O-methyl O-(4-methyl-2-nitrophenyl) ester
  • O-methyl O-(4-methyl-2-nitrophenyl) isopropylthiophosphorami...
  • 36001-88-4
  • C11H17N2O4PS
  • Biochemicals and Reagents
  • BioChemical
  • Enzymes, Inhibitors, and Substrates
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  • Enzyme Inhibitors
  • Substrate Analogs