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AMIPROFOS METHYL

Product Name
AMIPROFOS METHYL
CAS No.
36001-88-4
Chemical Name
AMIPROFOS METHYL
Synonyms
ntn80;ntn6867;bayntn80;NTN-2925;Tokunol-M;bayntn6867;amiprophosmethyl;AMIPROFOS METHYL;Amiprofosmethylbiochemika;O-METHYL O-(2-NITRO-P-TOLYL) N-ISOPROPYL-PHOSPHORAMIDOTHIONATE
CBNumber
CB6124212
Molecular Formula
C11H17N2O4PS
Formula Weight
304.3
MOL File
36001-88-4.mol
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AMIPROFOS METHYL Property

Melting point:
~65 °C
Boiling point:
146.6°C
Density 
1.275±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-0.73±0.70(Predicted)
form 
Solid
color 
White to Off-White
BRN 
2000833
EPA Substance Registry System
Amiprofos-methyl (36001-88-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
TB5100000
Toxicity
LD50 orl-rat: 309 mg/kg 85AREA 2,212,77
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
03992
Product name
Amiprofos methyl
Purity
PESTANAL , analytical standard
Packaging
50mg
Price
$237
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
10mg
Price
$60
Updated
2023/06/20
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
50mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
23379
Product name
Amiprofos methyl
Purity
≥98%
Packaging
100mg
Price
$185
Updated
2024/03/01
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AMIPROFOS METHYL Chemical Properties,Usage,Production

Description

Amiprofos-methyl (APM) is a phosphoric amide herbicide. It reversibly decreases H. vulgare root and shoot length and inhibits in vitro polymerization of Rosa tubulin induced by paclitaxel in a dose-dependent manner. APM completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM. The antitubulin effects of APM are specific to plants as it has no effect on bovine brain tubulin polymerization at concentrations up to 100 μM. APM inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM. APM inhibits the growth of P. falciparum (IC50 = 3.5 μM) and completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM.

Uses

Amiprofos-methyl is useful in herbicide compositions.

Biochem/physiol Actions

Herbicide that prevents microtubule polymerization in plant cells, but not animal cells. Crop plants resistant to amiprofos-methyl and several other herbicides have been developed by insertion of a xenobiotic-detoxifying human gene CYP2B6.

Safety Profile

A poison by ingestion. Lowtoxicity by skin contact. When heated to decomposition itemits toxic vapors of NOx, SOx, and POx.

AMIPROFOS METHYL Preparation Products And Raw materials

Raw materials

Basic Orange 2 O-methyl dichlorothiophosphate 2-Nitro-p-cresol Isopropylamine

Preparation Products

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AMIPROFOS METHYL Suppliers

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36001-88-4, AMIPROFOS METHYLRelated Search:

Pyriproxyfen Paraquat water AMIPROPHOS AMIPROFOS METHYL O,O-Dimethyl phosphoramidothioate

  • amiprophosmethyl
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  • n-isopropyl-phosphoramidothioicacio-methylo-(2-nitro-p-tolyl)ester
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  • AMIPROFOS METHYL
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  • O-methyl O-(4-methyl-2-nitrophenyl) isopropylthiophosphoramidate
  • Amiprofosmethylbiochemika
  • O-methyl-O-(2-nitro-4-methylpehnyl)-N-isopropylphosphoramidothioate
  • Tokunol-M
  • N-Isopropylphosphoramidothioic acid O-methyl O-(4-methyl-2-nitrophenyl)
  • NTN-2925
  • Amiprofos methyl,O-Methyl O-(2-nitro-p-tolyl) N-isopropylphosphoramidothionate
  • Phosphoramidothioic acid, N-(1-methylethyl)-, O-methyl O-(4-methyl-2-nitrophenyl) ester
  • O-methyl O-(4-methyl-2-nitrophenyl) isopropylthiophosphorami...
  • 36001-88-4
  • C11H17N2O4PS
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