Akebia saponin D

Product Name: Akebia saponin D
CAS No.: 39524-08-8
Chemical Name: Akebia saponin D
Synonyms: Asperosap;AkebosideD;Asperosaponin Ⅵ;Asperosaponin VI;Akebia saponin D;Dipsacaceae saponin;Asperosaponin VI-RM;Akebia saponin D USP/EP/BP;Asperosaponin VI (Akeboside D);Asperosaponin VI, 10 mM in DMSO
CBNumber: CB61267734
Molecular Formula: C47H76O18
Formula Weight: 929.1
MOL File: 39524-08-8.mol

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Akebia saponin D Property

Melting point:: 234-235 °C
Boiling point:: 990.2±65.0 °C(Predicted)
Density: 1.43
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form: Solid
pka: 12.50±0.70(Predicted)
color: White to Pale Beige
optical activity: [α]/D +13 to +18°, c =0.5 in methanol
biological source: (Dipsacus asper)
Water Solubility: H2O: 3mg/mL, clear (warmed)

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Safety

Safety Statements: 24/25
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83275
Product name: Asperosaponin VI
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $550
Updated: 2024/03/01

TRC

Product number: A788600
Product name: AsperosaponinVI
Packaging: 10mg
Price: $150
Updated: 2021/12/16

Usbiological

Product number: 299958
Product name: Asperosaponin VI
Packaging: 20mg
Price: $390
Updated: 2021/12/16

ChemScene

Product number: CS-0008286
Product name: AsperosaponinVI
Purity: 98.73%
Packaging: 20mg
Price: $150
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb104638
Product name: Akebia saponin D
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

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Akebia saponin D Chemical Properties,Usage,Production

Uses

Asperosaponin VI is a steroidal extract with anti-inflammatory and antinociceptive activity. long term use has been seen to attenuate cardiac dysfunction.

Definition

ChEBI: Akebia saponin D is a triterpenoid saponin that is hederagenin attached to a alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage and a 6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 28 via an ester linkage. It is the active ingredient found in the traditional Chinese herb Radix Dipsaci. It has a role as an apoptosis inducer, an antineoplastic agent, a plant metabolite, an anti-inflammatory agent, a bone density conservation agent, a neuroprotective agent and an antilipemic drug. It is a triterpenoid saponin, a trisaccharide derivative, a pentacyclic triterpenoid and a carboxylic ester. It is functionally related to a hederagenin.

Biological Activity

Akebia saponin D (ASD) is a bioactive triterpenoid saponin isolated from the rhizome of Dipsacus asper Wall th at is used as an anti-osteoporosis drug. Akebia saponin D exhibits therapeutic effects in number of disease models including cancer, Alzheimerμs disease, cardiovascular disease, and bone fractures. Akebia saponin D protects against nonalcoholic fatty liver disease (NAFLD) liver damage in mice model of NAFLD. ASD decreases hepatic steatosis and heptocyte apoptosis through autophagy modulation. Akebia saponin D prevents oleic acid induced lipid droplets accumulation and increases autophagic flux BRL cells.

Akebia saponin D Preparation Products And Raw materials

Raw materials

Preparation Products

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Akebia saponin D Suppliers

China 175 India 1 United Kingdom 1 United States 15 Global 192

ZHIWE CHEMTECH CO LTD

Tel: 021-20221225 13917446399
Fax: QQ:115820162
Email: sales@zhiwe.net
Country: China
ProdList: 628
Advantage: 61

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
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Adamas Reagent, Ltd.

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Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
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Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
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Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

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Country: China
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BioBioPha Co., Ltd.

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ShangHai YuanYe Biotechnology Co., Ltd.

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Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

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View Lastest Price from Akebia saponin D manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Akebia saponin D 39524-08-8
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-29

Shanghai Standard Technology Co., Ltd.

Product: Akebia saponin D 39524-08-8
Price: US $0.00/mg
Min. Order: 5mg
Purity: Analytical Standard
Supply Ability: 10 g
Release date: 2019-09-29

Career Henan Chemical Co

Product: Akebia saponin D 39524-08-8
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10000kg
Release date: 2018-08-10

39524-08-8, Akebia saponin DRelated Search:

Pennogenin 3-O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl-(1-4)-beta-D-glucopyranoside 4'-O-Acetyl-akebia saponin D Dipsanoside A 3-[[2-O-(α-L-Rhamnopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid Dipsanoside B oleanolic acid-3-O-β-D-glucopyranosyl (1→2)-α-L-arabinopyranoside Sylvestroside I dipsacoside B (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside TRIBULOSIDE Saponin

Akebia saponin D

Asperosaponin VI

Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1→6)-beta-D-glucopyranoside

Akebia saponin D(Asperosaponin VI)

Dipsacaceae saponin

3'-Amino-2'-Hydroxy-1,1' biphenyl-3-cAsperosaponin VI

Asperosaponin VI, 98%, from Dipsacales

Asperosaponin Ⅵ

Asperosaponin VI (Akeboside D)

AkebosideD

Olean-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-23-hydroxy-, 6-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (3β,4α)-

Akebia saponin D USP/EP/BP

TIANFUCHEM--39524-08-8--High purity Akebia saponin D factory price

Asperosap

1-O-[(3b)-3-(a-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-b-D-glucopyranose

(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

Asperosaponin VI-RM

3’-Amino-2’-Hydroxy-1,1’ biphenyl-3-cAsperosaponin VI

Asperosaponin VI, 10 mM in DMSO

39524-08-8

C47H76O18

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract