ChemicalBook > CAS DataBase List > PIPERIDOLATE HYDROCHLORIDE

PIPERIDOLATE HYDROCHLORIDE

Product Name: PIPERIDOLATE HYDROCHLORIDE
CAS No.: 129-77-1
Chemical Name: PIPERIDOLATE HYDROCHLORIDE
Synonyms: Crapinon;NSC 4349;Dihyprylone;Piperidolate HCl;dactilhydrochloride;PIPERIDOLATE HYDROCHLORIDE;3,3-Diethyl-2,4-piperidinedione;Piperidolate Hydrochloride (200 mg);Piperidolate Hydrochloride (1543006);Piperidolate hydrochloride, 10 mM in DMSO
CBNumber: CB6126948
Molecular Formula: C21H26ClNO2
Formula Weight: 359.89
MOL File: 129-77-1.mol

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PIPERIDOLATE HYDROCHLORIDE Property

Melting point:: 195-196°
storage temp.: Store at -20°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-4446
Product name: Piperidolatehydrochloride
Purity: 99.94%
Packaging: 100mg
Price: $228
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0012877
Product name: PIPERIDOLATE HYDROCHLORIDE
Purity: 98.00%
Packaging: 10MG
Price: $280.35
Updated: 2021/12/16

ChemScene

Product number: CS-4446
Product name: Piperidolatehydrochloride
Purity: 99.94%
Packaging: 200mg
Price: $312
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0012877
Product name: PIPERIDOLATE HYDROCHLORIDE
Purity: 98.00%
Packaging: 250G
Price: $4548.39
Updated: 2021/12/16

Crysdot

Product number: CD31003974
Product name: Piperidolatehydrochloride
Purity: 98+%
Packaging: 100mg
Price: $132
Updated: 2021/12/16

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PIPERIDOLATE HYDROCHLORIDE Chemical Properties,Usage,Production

Originator

Dactil, Merrell National ,US ,1954

Uses

Piperidolate Hydrochloride acts as an anticholinergic agent. Also a potential inhibitor of human glutathione transferase P1-1.

Definition

ChEBI: Piperidolate hydrochloride is a diarylmethane.

Manufacturing Process

To obtain the free base, 34 g (0.256 mol) of N-ethyl-3-piperidinol and 20 g (0.22 mol) of diphenylacetyl chloride were mixed in 80 cc of isopropanol and the solution was refluxed for 2 hours. The isopropanol was evaporated in vacuo at 30 mm pressure, the residue was dissolved in 150 cc of water and the aqueous solution was extracted several times with ether. The aqueous solution was then neutralized with potassium carbonate and extracted withether. The ethereal solution was dried over anhydrous potassium carbonate and the ether removed by distillation. The product was then distilled at its boiling point 180° to 181°C at 0.13 mm of mercury whereby 14 g of a clear yellow, viscous liquid was obtained. The nitrogen content for C21H25NO2 was calculated as 4.33% and the nitrogen content found was 4.21%.
The starting material was produced by the reaction of furfural with ethylamine followed by hydrogenation to give N-ethyl-N-(2-tetrahydrofurfuryl)amine. Treatment of that material with hydrogen bromide in acetic acid gives N-ethyl3-piperidinol.

brand name

Dactil (Marion Merrell Dow).

Therapeutic Function

Spasmolytic

PIPERIDOLATE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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129-77-1, PIPERIDOLATE HYDROCHLORIDERelated Search:

PIPERIDOLATE 1-ETHYL-3-HYDROXYPIPERIDINE 3-Hydroxy-1-methylpiperidine 2,2-Diphenylacetic acid 3-ETHOXYPIPERIDINE 3-Hydroxypiperidine 3-Hydroxypiperidine hydrochloride PIPERIDOLATE HYDROCHLORIDE Adiphenine hydrochloride 3-METHOXYPIPERIDINE DIPHENYL-ACETIC ACID ETHYL ESTER 3-METHOXY-PIPERIDINE HYDROCHLORIDE 3-PROPOXY-PIPERIDINE 2,2-Diphenyl-2-methoxyacetic acid (1-ethyl-3-piperidyl) ester hydrochl oride 3-(9-Xanthenylcarboxy)quinuclidine hydrochloride ACETIC ACID, PHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER 2-(Dimethylamino)ethyl diphenylacetate hydrochloride N-METHYL L-QNB, [N-METHYL-3H]-

aceticacid,diphenyl-,1-ethyl-3-piperidylester,hydrochloride

benzeneaceticacid,alpha-phenyl-,1-ethyl-3-piperidinylester,hydrochloride

benzeneaceticacid,alpha-phenyl-,1-ethyl-3-piperidylester,hydrochloride

dactilhydrochloride

diphenylaceticacid,1-ethyl-3-piperidylesterhydrochloride

n-ethyl-3-piperidyldiphenylacetatehydrochloride

PIPERIDOLATE HYDROCHLORIDE

3,3-Diethyl-2,4-piperidinedione

Dihyprylone

3-Piperidinol, 1-ethyl-, diphenylacetate (ester), hydrochloride (8CI)

Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester hydrochloride (6CI, 7CI, 8CI)

Benzeneacetic acid, a-phenyl-, 1-ethyl-3-piperidinyl ester, hydrochloride (9CI)

Crapinon

NSC 4349

1-ethyl-3-piperidyldiphenyl-acetatehydrochloride

3-piperidinol,1-ethyl-,diphenylacetate,hydrochloride

Piperidolate Hydrochloride (200 mg)

α-Phenylbenzeneacetic acid 1-ethyl-3-piperidinyl ester monohydrochloride

1-Ethylpiperidin-3-yl 2,2-diphenylacetate hydrochloride

Piperidolate HCl

Piperidolate Hydrochloride (1543006)

Inhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidolate hydrochloride,mAChR

Piperidolate hydrochloride, 10 mM in DMSO

129-77-1

C21H25NO2HCl