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PIPERIDOLATE HYDROCHLORIDE

Product Name
PIPERIDOLATE HYDROCHLORIDE
CAS No.
129-77-1
Chemical Name
PIPERIDOLATE HYDROCHLORIDE
Synonyms
Crapinon;NSC 4349;Dihyprylone;Piperidolate HCl;dactilhydrochloride;PIPERIDOLATE HYDROCHLORIDE;3,3-Diethyl-2,4-piperidinedione;Piperidolate Hydrochloride (200 mg);Piperidolate Hydrochloride (1543006);n-ethyl-3-piperidyldiphenylacetatehydrochloride
CBNumber
CB6126948
Molecular Formula
C21H26ClNO2
Formula Weight
359.89
MOL File
129-77-1.mol
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PIPERIDOLATE HYDROCHLORIDE Property

Melting point:
195-196°
storage temp. 
Store at -20°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-4446
Product name
Piperidolatehydrochloride
Purity
99.94%
Packaging
100mg
Price
$228
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012877
Product name
PIPERIDOLATE HYDROCHLORIDE
Purity
98.00%
Packaging
10MG
Price
$280.35
Updated
2021/12/16
ChemScene
Product number
CS-4446
Product name
Piperidolatehydrochloride
Purity
99.94%
Packaging
200mg
Price
$312
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012877
Product name
PIPERIDOLATE HYDROCHLORIDE
Purity
98.00%
Packaging
250G
Price
$4548.39
Updated
2021/12/16
Crysdot
Product number
CD31003974
Product name
Piperidolatehydrochloride
Purity
98+%
Packaging
100mg
Price
$132
Updated
2021/12/16
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PIPERIDOLATE HYDROCHLORIDE Chemical Properties,Usage,Production

Originator

Dactil, Merrell National ,US ,1954

Uses

Piperidolate Hydrochloride acts as an anticholinergic agent. Also a potential inhibitor of human glutathione transferase P1-1.

Definition

ChEBI: Piperidolate hydrochloride is a diarylmethane.

Manufacturing Process

To obtain the free base, 34 g (0.256 mol) of N-ethyl-3-piperidinol and 20 g (0.22 mol) of diphenylacetyl chloride were mixed in 80 cc of isopropanol and the solution was refluxed for 2 hours. The isopropanol was evaporated in vacuo at 30 mm pressure, the residue was dissolved in 150 cc of water and the aqueous solution was extracted several times with ether. The aqueous solution was then neutralized with potassium carbonate and extracted withether. The ethereal solution was dried over anhydrous potassium carbonate and the ether removed by distillation. The product was then distilled at its boiling point 180° to 181°C at 0.13 mm of mercury whereby 14 g of a clear yellow, viscous liquid was obtained. The nitrogen content for C21H25NO2 was calculated as 4.33% and the nitrogen content found was 4.21%.
The starting material was produced by the reaction of furfural with ethylamine followed by hydrogenation to give N-ethyl-N-(2-tetrahydrofurfuryl)amine. Treatment of that material with hydrogen bromide in acetic acid gives N-ethyl3-piperidinol.

brand name

Dactil (Marion Merrell Dow).

Therapeutic Function

Spasmolytic

PIPERIDOLATE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PIPERIDOLATE HYDROCHLORIDE Suppliers

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129-77-1, PIPERIDOLATE HYDROCHLORIDERelated Search:


  • aceticacid,diphenyl-,1-ethyl-3-piperidylester,hydrochloride
  • benzeneaceticacid,alpha-phenyl-,1-ethyl-3-piperidinylester,hydrochloride
  • benzeneaceticacid,alpha-phenyl-,1-ethyl-3-piperidylester,hydrochloride
  • dactilhydrochloride
  • diphenylaceticacid,1-ethyl-3-piperidylesterhydrochloride
  • n-ethyl-3-piperidyldiphenylacetatehydrochloride
  • PIPERIDOLATE HYDROCHLORIDE
  • 3,3-Diethyl-2,4-piperidinedione
  • Dihyprylone
  • 3-Piperidinol, 1-ethyl-, diphenylacetate (ester), hydrochloride (8CI)
  • Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester hydrochloride (6CI, 7CI, 8CI)
  • Benzeneacetic acid, a-phenyl-, 1-ethyl-3-piperidinyl ester, hydrochloride (9CI)
  • Crapinon
  • NSC 4349
  • 1-ethyl-3-piperidyldiphenyl-acetatehydrochloride
  • 3-piperidinol,1-ethyl-,diphenylacetate,hydrochloride
  • Piperidolate Hydrochloride (200 mg)
  • α-Phenylbenzeneacetic acid 1-ethyl-3-piperidinyl ester monohydrochloride
  • 1-Ethylpiperidin-3-yl 2,2-diphenylacetate hydrochloride
  • Piperidolate HCl
  • Piperidolate Hydrochloride (1543006)
  • Inhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidolate hydrochloride,mAChR
  • 129-77-1
  • C21H25NO2HCl