PIPERIDOLATE HYDROCHLORIDE
- Product Name
- PIPERIDOLATE HYDROCHLORIDE
- CAS No.
- 129-77-1
- Chemical Name
- PIPERIDOLATE HYDROCHLORIDE
- Synonyms
- Crapinon;NSC 4349;Dihyprylone;Piperidolate HCl;dactilhydrochloride;PIPERIDOLATE HYDROCHLORIDE;3,3-Diethyl-2,4-piperidinedione;Piperidolate Hydrochloride (200 mg);Piperidolate Hydrochloride (1543006);n-ethyl-3-piperidyldiphenylacetatehydrochloride
- CBNumber
- CB6126948
- Molecular Formula
- C21H26ClNO2
- Formula Weight
- 359.89
- MOL File
- 129-77-1.mol
PIPERIDOLATE HYDROCHLORIDE Property
- Melting point:
- 195-196°
- storage temp.
- Store at -20°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-4446
- Product name
- Piperidolatehydrochloride
- Purity
- 99.94%
- Packaging
- 100mg
- Price
- $228
- Updated
- 2021/12/16
- Product number
- API0012877
- Product name
- PIPERIDOLATE HYDROCHLORIDE
- Purity
- 98.00%
- Packaging
- 10MG
- Price
- $280.35
- Updated
- 2021/12/16
- Product number
- CS-4446
- Product name
- Piperidolatehydrochloride
- Purity
- 99.94%
- Packaging
- 200mg
- Price
- $312
- Updated
- 2021/12/16
- Product number
- API0012877
- Product name
- PIPERIDOLATE HYDROCHLORIDE
- Purity
- 98.00%
- Packaging
- 250G
- Price
- $4548.39
- Updated
- 2021/12/16
- Product number
- CD31003974
- Product name
- Piperidolatehydrochloride
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $132
- Updated
- 2021/12/16
PIPERIDOLATE HYDROCHLORIDE Chemical Properties,Usage,Production
Originator
Dactil, Merrell National ,US ,1954
Uses
Piperidolate Hydrochloride acts as an anticholinergic agent. Also a potential inhibitor of human glutathione transferase P1-1.
Definition
ChEBI: Piperidolate hydrochloride is a diarylmethane.
Manufacturing Process
To obtain the free base, 34 g (0.256 mol) of N-ethyl-3-piperidinol and 20 g (0.22 mol) of diphenylacetyl chloride were mixed in 80 cc of isopropanol and the solution was refluxed for 2 hours. The isopropanol was evaporated in vacuo at 30 mm pressure, the residue was dissolved in 150 cc of water and the aqueous solution was extracted several times with ether. The aqueous solution was then neutralized with potassium carbonate and extracted withether. The ethereal solution was dried over anhydrous potassium carbonate and the ether removed by distillation. The product was then distilled at its boiling point 180° to 181°C at 0.13 mm of mercury whereby 14 g of a clear yellow, viscous liquid was obtained. The nitrogen content for C21H25NO2 was calculated as 4.33% and the nitrogen content found was 4.21%.
The starting material was produced by the reaction of furfural with ethylamine followed by hydrogenation to give N-ethyl-N-(2-tetrahydrofurfuryl)amine. Treatment of that material with hydrogen bromide in acetic acid gives N-ethyl3-piperidinol.
brand name
Dactil (Marion Merrell Dow).
Therapeutic Function
Spasmolytic
PIPERIDOLATE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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