ChemicalBook > CAS DataBase List > (1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride

(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride

Product Name
(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride
CAS No.
87269-87-2
Chemical Name
(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride
Synonyms
Ramipril Intermediate;Ramipril Intermediate2;(2S,3aS,6aS)-Octahydrocyclopenta[b];Imidapril Impurity 19(Hydrochloride);(S,S,S)-2-AZABICYCLO (3,3,0) OCTANE CAR&;Benzyl (cis, endo) octahydrocyclopenta (Ramipril int);(3S)-BENZYL ENDO CIS-2-AZABICYCLO (3,3,0)-OCTANE HYDROCHLORIDE;(1s,3s,5s)-2-azabicyclo(3,3,0)octane-3-carboxylic acid benzy...;(1s,3s,5s)-2-azabicyclo(3,3,0)octane-3-carborylic acid benzyl ester;BENZYL (S,S,S)-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLATE HYDROCHLORIDE
CBNumber
CB6129000
Molecular Formula
C15H20ClNO2
Formula Weight
281.78
MOL File
87269-87-2.mol
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(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride Property

Melting point:
176-180 °C(lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly, Heated), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
optical activity
[α]20/D -26°, c = 1% in DMSO
Stability:
Hygroscopic
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2933.99.9701
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
570907
Product name
Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride
Purity
97%
Packaging
5g
Price
$634
Updated
2023/06/20
Sigma-Aldrich
Product number
570907
Product name
Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride
Purity
97%
Packaging
1g
Price
$133
Updated
2023/01/07
TCI Chemical
Product number
B5344
Product name
Benzyl (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylate Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$70
Updated
2024/03/01
TCI Chemical
Product number
B5344
Product name
Benzyl (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylate Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$277
Updated
2024/03/01
TRC
Product number
A795273
Product name
(S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylicAcid,BenzylEster,Hydrochloride
Packaging
1g
Price
$45
Updated
2021/12/16
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(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Thick Yellow Oil

Uses

Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride can be used:

  • In the preparation of ramipril, an angiotensin-converting enzyme (ACE) inhibitor.
  • As a starting material for the synthesis of octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as potent DPP4 inhibitors.

Uses

In intermediate in the synthesis of Ramipril

(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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XiaoGan ShenYuan ChemPharm co,ltd
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15527768850
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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sales@heowns.com
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China
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Shanghai Topbiochem Technology Co., Ltd
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+86-21-60341587
Fax
+86-21-61294319
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sales@topbiochem.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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View Lastest Price from (1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Imidapril Impurity 19(Hydrochloride) 87269-87-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-08-06
Hangzhou ICH Biofarm Co., Ltd
Product
(1S,3S,5S)-2-Azabicyclo[3,3,0] –octan-carboxylic acid benzylester hydrochloride 87269-87-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.0%
Supply Ability
20 tons
Release date
2023-06-27
Career Henan Chemical Co
Product
(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride 87269-87-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

87269-87-2, (1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochlorideRelated Search:


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  • (S,S,S)-2-AZABICYCLO (3,3,0) OCTANE CAR&
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  • (1s,3s,5s)-2-azabicyclo(3,3,0)octane-3-carborylic acid benzyl ester
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  • (S,S,S)-2-Azabicyclo[3,3,0]-Octane-Carboxylic Acid Benzyl Ester Hydroxychloride
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  • (1S, 3S, 5S) -2-azabicyclic [3,3,0] octane-3-carboxylic acid benzyl ester hydrochloride
  • Benzyl (cis, endo) octahydrocyclopenta (Ramipril int)
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  • (1S, 3S, 5S) -2-Azabicyclo [3,3,0] octane-3-carboxylate benzyl ester hydrochloride
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  • Imidapril Impurity 19(Hydrochloride)
  • 87269-87-2
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  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical Intermediates