BOC-BETA-CYCLOHEXYL-ALA-OH

Product Name: BOC-BETA-CYCLOHEXYL-ALA-OH
CAS No.: 37736-82-6
Chemical Name: BOC-BETA-CYCLOHEXYL-ALA-OH
Synonyms: BOC-CHA-OH;BOC-L-CHA-OH;Boc-L-Cha-OH (Oil);BOC-L-CYCLOHEXYLALANINE;Boc-β-cyclohexyl-ala-OH;Boc-b-cyclohexyl-Ala-OH;BOC-BETA-CYCLOHEXYL-ALA-OH;BOC-3-CYCLOHEXYL-L-ALANINE;Boc-β-cyclohexyl-L-alanine;BOC-L-3-Cyclohexyl Alanine
CBNumber: CB6129914
Molecular Formula: C14H25NO4
Formula Weight: 271.35
MOL File: 37736-82-6.mol

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BOC-BETA-CYCLOHEXYL-ALA-OH Property

Boiling point:: 420.4±28.0 °C(Predicted)
Density: 1.083±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 4.02±0.10(Predicted)
form: <40°C Solid,>42°C Liquid
Appearance: White to off-white <40°C Solid,>42°C Liquid
optical activity: [α]20/D 15.5±1°, c = 2% in glacial acetic acid
BRN: 3060603
InChI: InChI=1/C14H25NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h10-11H,4-9H2,1-3H3,(H,15,18)(H,16,17)/t11-/s3
InChIKey: MSZQAQJBXGTSHP-NSHDSACASA-N
SMILES: [C@H](C(=O)O)(NC(=O)OC(C)(C)C)CC1CCCCC1 |&1:0,r|
CAS DataBase Reference: 37736-82-6(CAS DataBase Reference)

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Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4244
Product name: Boc-Cha-OH
Packaging: 5G
Price: $141
Updated: 2025/07/31

TCI Chemical

Product number: B4244
Product name: Boc-Cha-OH
Packaging: 25G
Price: $424
Updated: 2025/07/31

TRC

Product number: B693540
Product name: N-(tert-Butyloxycarbonyl)-L-cyclohexylalanine
Packaging: 1g
Price: $115
Updated: 2021/12/16

Usbiological

Product number: 266502
Product name: Boc-beta-cyclohexyl-L-alanine
Packaging: 2g
Price: $337
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB55872
Product name: Boc-beta-cyclohexyl-L-alanine
Packaging: 50g
Price: $350
Updated: 2021/12/16

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BOC-BETA-CYCLOHEXYL-ALA-OH Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

It is an agrochemical, organic and pharmaceutical intermediates.

Synthesis

24424-99-5

25528-71-6

37736-82-6

Step 2. Synthesis of (S)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropionic acid. (S)-2-amino-3-cyclohexylpropanoic acid hydrochloride (118 g, 0.57 mol) was dissolved in 0.5 N NaOH aqueous solution (1200 mL), followed by the addition of a solution of tetrahydrofuran (THF, 600 mL) of di-tert-butyl dicarbonate (Boc2O, 137 g, 0.63 mol). The reaction mixture was stirred for 2 hours. After completion of the reaction, the organic solvent was removed under reduced pressure. The aqueous phase was washed with ether (Et2O, 2 x 400 mL) to remove unreacted feedstock. Subsequently, the aqueous phase was acidified to pH 5 with aqueous 2 N HCl. The acidified aqueous phase was extracted with ethyl acetate (EtOAc, 3 × 400 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give the title compound (S)-2-((tert-butoxycarbonyl)amino)-3-cyclohexylpropanoic acid (142 g, 92%) as an oil.1H NMR (CDCl3) δ: 0.92 (m, 1H), 1.09-1.30 (m, 3H), 1.48 (s, 9H), 1.51 (m, 1H), 1.52 (m, 1H), 1.66 (m, 5H), 1.78 (m, 1H), 4.32 (m, 1H), 4.88 (m, 1H), 8.55-9.48 (br s, 1H).

References

[1] Journal of Antibiotics, 1996, vol. 49, # 9, p. 909 - 920
[2] Patent: WO2007/117557, 2007, A2. Location in patent: Page/Page column 91
[3] Patent: US5756763, 1998, A

BOC-BETA-CYCLOHEXYL-ALA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-BETA-CYCLOHEXYL-ALA-OH Suppliers

China 134 France 1 Germany 4 India 2 Japan 2 South Korea 1 Switzerland 1 United Kingdom 5 United States 17 Global 167

Tebu-bio

Tel: --
Fax: --
Email: gilles.cestelli@tebu-bio.com
Country: France
ProdList: 251
Advantage: 75

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View Lastest Price from BOC-BETA-CYCLOHEXYL-ALA-OH manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: BOC-BETA-CYCLOHEXYL-ALA-OH 37736-82-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

37736-82-6, BOC-BETA-CYCLOHEXYL-ALA-OHRelated Search:

Boc-D-Phenylglycine Boc-beta-cyclohexyl-D-alanine monohydrate BOC-D-ABU-OH BOC-ABU-OH Boc-L-Cyclohexylglycine (S)-2-((tert-butoxycarbonyl)amino)-4-cyclohexylbutanoic acid Boc-D-Serine Boc-alpha-Cyclohexyl-D-glycine BOC-OIC-OH BOC-CHA-OH DCHA L-Cyclohexylalanine BOC-BETA-CYCLOHEXYL-ALA-OH BOC-L-CYCLOHEXYLALANINE HYDROXYSUCCINIMIDE ESTER BOC-3-CYCLOHEXYL-L-ALANINE METHYL ESTER BOC-L-MECHA-OH BOC-L-CYCLOHEXYLALANINE 2H2O (3S,4AR,8AR)-N-BOC-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (3S,4AS,8AS)-N-BOC-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID

(S)-2-TERT-BUTOXYCARBONYLAMINO-3-CYCLOHEXYL-PROPIONIC ACID

BOC-L-CYCLOHEXYLALANINE

BOC-L-CHA-OH

BOC-3-CYCLOHEXYL-L-ALANINE

BOC-BETA-CYCLOHEXYL-ALANINE

BOC-CHA-OH

BOC-BETA-CYCLOHEXYL-ALA-OH

BOC-BETA-CYCLOHEXYL-L-ALANINE

N-T-boc-B-cyclohexyl-L-alanine

Boc-β-cyclohexyl-ala-OH

(S)-2-(Boc-amino)-3-cyclohexylpropionic Acid

(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-cyclohexylpropanoic acid

(S)-2-(Tert-butoxycarbonylaMino)-3-cyclohexylpropanoic acid hydrate

N-Boc-3-cyclohexyl-L-alanine, 98%

Boc-b-cyclohexyl-Ala-OH

Boc-(S)-3-Cyclohexylalanine

Boc-β-cyclohexyl-L-alanine

(S)-2-((tert-Butoxycarbonyl)aMino)-3-cyclohexylpropanoic acid

Boc-Cha-OH hydrate >=99.0% (TLC), ~1 mol/mol water

BOC-L-3-Cyclohexyl Alanine

Boc-?-cyclohexyl-L-alanine99%

(Tert-Butoxy)Carbonyl Cha-OH

NALPHA-tert-Butoxycarbonyl-3-cyclohexyl-L-alanine

(S)-N-alpha-t-Butyloxycarbonyl-3-(cyclohexyl)-alanine (oil)

Boc-L-Cha-OH (Oil)

N-(tert-butoxycarbonyl)-beta-cyclohexyl-L-alanine

Boc-3-cyclohexyl-L-alanine hydrate, Boc-hexahydro-L-phenylalanine

BOC--Cyclohexyl Ala-OH hydrate

Boc-hexahydro-L-phenylalanine

Cyclohexanepropanoic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-,(aS)-

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoicaci

BOC-BETA-CYCLOHEXYL-ALA-OH USP/EP/BP

(S)-N-alpha-t-Butyloxycarbonyl-3-(cyclohexyl)-alanine

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoic

Cyclohexanepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)-

Boc-beta-cyclohexyl-L-alanine - 5 g

37736-82-6

C14H25NO4

Alanine Derivatives

Specialty Synthesis

Peptide Synthesis

Unnatural Amino Acid Derivatives

Peptide

Amino Acids

pharmacetical