ChemicalBook > CAS DataBase List > L 741626
L 741626
- Product Name
- L 741626
- CAS No.
- 81226-60-0
- Chemical Name
- L 741626
- Synonyms
- L-741626, 10 mM in DMSO;L-741,626, D2 antagonist;3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL;4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-;receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit
- CBNumber
- CB61320787
- Molecular Formula
- C20H21ClN2O
- Formula Weight
- 340.85
- MOL File
- 81226-60-0.mol
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L 741626 Property
- Boiling point:
- 548.8±50.0 °C(Predicted)
- Density
- 1.311±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- pka
- 13.87±0.20(Predicted)
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- L135
- Product name
- L-741,626
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $162
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- L135
- Product name
- L-741,626
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $683
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 5.05879
- Product name
- L-741,626 - CAS 81226-60-0 - Calbiochem
- Packaging
- 10mg
- Price
- $146
- Updated
- 2022/05/15
Cayman Chemical
- Product number
- 22354
- Product name
- L-741,626
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22354
- Product name
- L-741,626
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $116
- Updated
- 2024/03/01
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L 741626 Chemical Properties,Usage,Production
Uses
L-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists.
Uses
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
Definition
ChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines.
Hazard
A poison.
Biochem/physiol Actions
L-741,626 is a selective dopamine (D2) receptor antagonist.
storage
Store at RT
L 741626 Preparation Products And Raw materials
Raw materials
Preparation Products
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L 741626 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77