ChemicalBook > CAS DataBase List > 2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE

2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE

Product Name
2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE
CAS No.
37859-43-1
Chemical Name
2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE
Synonyms
2-(CHLOROMETHYL)BENZO[D]THIAZOLE;NSC 201711;BUTTPARK 77\08-26;CHEMBRDG-BB 4016924;2-CHLOROMETHYL-BENZOTHIAZOLE;Benzothiazole, 2-(chloromethyl)-;2-(Chloromethyl)benzothiazole,95%;2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE;Benzothiazole, 2-(chloromethyl)- (7CI,9CI)
CBNumber
CB6133283
Molecular Formula
C8H6ClNS
Formula Weight
183.66
MOL File
37859-43-1.mol
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2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE Property

Melting point:
34℃
Boiling point:
102°/0.5mm
Density 
1.371
Flash point:
120℃
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
soluble in Methanol
form 
Solid
pka
0.43±0.10(Predicted)
Appearance
Off-white to light yellow <34°C Solid,>34°C Liquid
Sensitive 
Moisture Sensitive
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-37/38-41-43
Safety Statements 
26-36/37-39
HazardClass 
IRRITANT
HS Code 
2934208090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3335
Product name
2-(Chloromethyl)benzothiazole
Purity
>98.0%(GC)
Packaging
1g
Price
$68
Updated
2025/07/31
TRC
Product number
C587915
Product name
2-(Chloromethyl)-1,3-benzothiazole
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
C587915
Product name
2-(Chloromethyl)-1,3-benzothiazole
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC134270
Product name
2-(Chloromethyl)-1,3-benzothiazole
Packaging
250mg
Price
$80
Updated
2021/12/16
AK Scientific
Product number
X0138
Product name
2-(Chloromethyl)-1,3-benzothiazole
Packaging
1g
Price
$93
Updated
2021/12/16
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2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE Chemical Properties,Usage,Production

Synthesis Reference(s)

Synthetic Communications, 19, p. 2921, 1989 DOI: 10.1080/00397918908052683

Synthesis

37859-42-0

37859-43-1

General procedure for the synthesis of 2-(chloromethyl)-1,3-benzothiazole from 2-hydroxymethylbenzothiazole: To a stirred solution containing 2-hydroxymethylbenzothiazole (2.5 g, 15.1 mmol), triphenylphosphine (4.89 g, 18.6 mmol), and anhydrous toluene (50 ml) was added, protected by nitrogen, carbon tetrachloride (15.0 ml, 155 mmol ). The reaction mixture was heated to reflux for 5 hours. After completion of the reaction, the reaction mixture was concentrated using a rotary evaporator to give the crude product. The crude product was purified by rapid chromatography on silica gel to afford 2-(chloromethyl)-1,3-benzothiazole (2.36 g, 85% yield) using 100% dichloromethane as eluent. The product was confirmed by mass spectrometry (ion spray): m/z = 183.9 (M + 1); 1H NMR (CDCl3) data were as follows: δ= 8.04-8.01 (1H, m), 7.91-7.89 (1H, m), 7.53-7.49 (1H, m), 7.44-7.40 (1H, m), 4.95 (2H, s).

References

[1] Tetrahedron, 1988, vol. 44, # 7, p. 2021 - 2032
[2] Chemical Communications, 2017, vol. 53, # 54, p. 7545 - 7548
[3] Patent: WO2005/92885, 2005, A1. Location in patent: Page/Page column 55
[4] Zhurnal Obshchei Khimii, 1954, vol. 24, p. 1664,1667; engl. Ausg. 1645, 1647
[5] Zhurnal Obshchei Khimii, 1956, vol. 26, p. 797,798; engl. Ausg. 911, 912

2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE Suppliers

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View Lastest Price from 2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE 37859-43-1
Price
US $31.00-1.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE 37859-43-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE 37859-43-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

37859-43-1, 2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLERelated Search:

Benzothiazole 3-chloromethyl-3h-benzothiazole-2-thione DIMETHYL 2-[1,3-BENZOTHIAZOL-2-YL(CHLORO)METHYLENE]-1,3-DITHIOLE-4,5-DICARBOXYLATE Benzothiazole, 2-(1-chloroethyl)- (9CI) Benzothiazole, 2-(chloromethyl)-4-fluoro- (9CI) 1,3-BENZOTHIAZOL-2-YL(DICHLORO)ACETONITRILE Benzothiazole, 2-(chloromethyl)-5-fluoro- (9CI) 1,3-BENZOTHIAZOLE-2-CARBONYL CHLORIDE 2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE

  • 2-(CHLOROMETHYL)-1,3-BENZOTHIAZOLE
  • 2-CHLOROMETHYL-BENZOTHIAZOLE
  • 2-(CHLOROMETHYL)BENZO[D]THIAZOLE
  • CHEMBRDG-BB 4016924
  • BUTTPARK 77\08-26
  • Benzothiazole, 2-(chloromethyl)- (7CI,9CI)
  • NSC 201711
  • Benzothiazole, 2-(chloromethyl)-
  • 2-(Chloromethyl)benzothiazole,95%
  • 37859-43-1
  • 34859-43-1
  • Building Blocks
  • C8 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • BENZOTHIAZOLE
  • Thiazoles