ChemicalBook > CAS DataBase List > YM 16638
YM 16638
- Product Name
- YM 16638
- CAS No.
- 104073-72-5
- Chemical Name
- YM 16638
- Synonyms
- YM-638;YM 16638;YM 638|||YM-16638|||YM16638;[[5-[[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]acetic acid;Acetic acid, 2-[[5-[[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]-;2-[[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]acetic acid
- CBNumber
- CB61359875
- Molecular Formula
- C18H22N2O5S3
- Formula Weight
- 442.57
- MOL File
- 104073-72-5.mol
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YM 16638 Property
- Melting point:
- 129-130 °C
- Boiling point:
- 682.6±65.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- pka
- 2.87±0.10(Predicted)
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YM 16638 Chemical Properties,Usage,Production
Uses
YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1].
References
[1] Tomioka K, et al. The effect of an orally active leukotriene (LT) antagonist YM-16638 on antigen-induced early and late airway responses in allergic sheep. Prostaglandins Leukot Essent Fatty Acids. 1989 Apr;36(1):43-7. DOI:10.1016/0952-3278(89)90161-0
YM 16638 Preparation Products And Raw materials
Raw materials
Preparation Products
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YM 16638 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
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