C 1311

Product Name: C 1311
CAS No.: 138154-39-9
Chemical Name: C 1311
Synonyms: C 1311;Symadex;XLS-002;Symadex >=98% (HPLC);CUNDRHORZHFPLY-UHFFFAOYSA-N;5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one;6H-Imidazo[4,5,1-de]acridin-6-one, 5-[[2-(diethylamino)ethyl]amino]-8-hydroxy-
CBNumber: CB61382587
Molecular Formula: C20H22N4O2
Formula Weight: 350.41
MOL File: 138154-39-9.mol

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C 1311 Property

Boiling point:: 605.8±65.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble10mg/mL (clear solution; warmed)
form: powder
pka: 8.35±0.20(Predicted)
color: white to beige

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0465
Product name: Symadex
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $143
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0465
Product name: Symadex
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $390
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: KIN0000064
Product name: C-1311
Purity: 95.00%
Packaging: 5MG
Price: $498.53
Updated: 2021/12/16

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C 1311 Chemical Properties,Usage,Production

Uses

C-1311 shows to inhibit the catalytic activity of DNA topoisomerase II in vitro and in tumour cells. C-1311 prolongs G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe[1].

Biological Activity

Symadex is an FMS-like tyrosine kinase 3 (FLT3) and topoisomerase-II inhibitor; ABCG2 substrate; cell cycle modulator.

References

[1] Magdalena Hyzy, et al. Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells. Biochem Pharmacol. 2005 Mar 1;69(5):801-9. DOI:10.1016/j.bcp.2004.11.028

C 1311 Preparation Products And Raw materials

Raw materials

Preparation Products

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C 1311 Suppliers

China 7 United States 3 Global 10

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

138154-39-9, C 1311Related Search:

Ethanone,1-(1H-benzimidazol-4-yl)- 2,2'-Diaminobenzophenone 1-[2-(1H-IMIDAZOL-1-YL)PHENYL]ETHANONE 4-(IMIDAZOL-1-YL)PHENOL 2-IMIDAZOL-1-YL-BENZALDEHYDE Imidazo[1,2-a]pyridine-2-carboxaldehyde 1-PHENYL-1H-BENZOIMIDAZOLE C 1311

C 1311

5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one

XLS-002

Symadex

CUNDRHORZHFPLY-UHFFFAOYSA-N

Symadex >=98% (HPLC)

6H-Imidazo[4,5,1-de]acridin-6-one, 5-[[2-(diethylamino)ethyl]amino]-8-hydroxy-

138154-39-9