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thielavin A

Product Name
thielavin A
CAS No.
71950-66-8
Chemical Name
thielavin A
Synonyms
thielavin A;4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester;Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
CBNumber
CB61386873
Molecular Formula
C29H30O10
Formula Weight
538.54
MOL File
71950-66-8.mol
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thielavin A Property

Melting point:
235-236 °C
Boiling point:
850.0±65.0 °C(Predicted)
Density 
1.371±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: souble; DMSO: souble; Ethanol: soluble
form 
White to off-white powder.
pka
2.82±0.28(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21767
Product name
Thielavin A
Purity
≥95%
Packaging
500μg
Price
$352
Updated
2024/03/01
Cayman Chemical
Product number
21767
Product name
Thielavin A
Purity
≥95%
Packaging
2.5mg
Price
$1402
Updated
2024/03/01
Usbiological
Product number
T5006-50
Product name
Thielavin A
Packaging
500ug
Price
$582
Updated
2021/12/16
TRC
Product number
T345095
Product name
ThielavinA
Packaging
1mg
Price
$735
Updated
2021/12/16
AK Scientific
Product number
2415CB
Product name
ThielavinA
Packaging
2.5mg
Price
$1660
Updated
2021/12/16
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thielavin A Chemical Properties,Usage,Production

Description

Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 (PGH2; ) and the conversion of PGH2 to PGE2 (; IC50s = 10 and 40 μM, respectively). Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

Uses

The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related thielavin B is a telomerase and cell wall transglycosylation inhibitor.

Uses

Thielavin A acts as an inhibitor of prostagladins biosynthesis.

thielavin A Preparation Products And Raw materials

Raw materials

Preparation Products

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thielavin A Suppliers

China 23 United Kingdom 1 United States 4 Global 28
Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Lynnchem
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86-(0)29-85992781 17792393971
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info@lynnchem.com
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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774
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sales@glpbio.cn
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6870
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 13028896684
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sales@rrkchem.com
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56039
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Meng Cheng Technology (Shanghai) Co., LTD
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400-820-6829
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sales@mitachieve.com
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China
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8864
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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025-85563444
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cindy.huang@synzest.com
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China
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TargetMol Chemicals Inc.
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15002134094
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marketing@targetmol.com
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China
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Beijing Bolide Biotechnology Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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Shanghai Bosheng Biotechnology Co., Ltd.
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Shanghai Yaoyun Biological Technology Co., Ltd.
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Beijing Lebo Biotechnology Co., Ltd.
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Xiamen Huijia Biological Technology Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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Beijing Fubo Biotechnology Co., Ltd.
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Shanghai Ziqi Biological Technology Co., Ltd.
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Boao Pike
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Shenzhen Xinbosheng Biological Technology Co., Ltd.
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71950-66-8, thielavin ARelated Search:

thielocin B3 PS 990 GYROPHORIC ACID EVERNIC ACID 4-BENZYLOXY-3,5-DIMETHYLBENZALDEHYDE 4-Benzyloxy-3,5-dimethylbenzoic acid thielavin A thielavin B CHEMBRDG-BB 9070990 2,5-dimethylphenyl 4-methoxybenzoate CHEMBRDG-BB 9072034

  • thielavin A
  • 4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
  • Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
  • 71950-66-8