ChemicalBook > CAS DataBase List > thielavin A

thielavin A

Product Name
thielavin A
CAS No.
71950-66-8
Chemical Name
thielavin A
Synonyms
thielavin A;4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester;Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
CBNumber
CB61386873
Molecular Formula
C29H30O10
Formula Weight
538.54
MOL File
71950-66-8.mol
More
Less

thielavin A Property

Melting point:
235-236 °C
Boiling point:
850.0±65.0 °C(Predicted)
Density 
1.371±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: souble; DMSO: souble; Ethanol: soluble
form 
White to off-white powder.
pka
2.82±0.28(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
21767
Product name
Thielavin A
Purity
≥95%
Packaging
500μg
Price
$352
Updated
2024/03/01
Cayman Chemical
Product number
21767
Product name
Thielavin A
Purity
≥95%
Packaging
2.5mg
Price
$1402
Updated
2024/03/01
Usbiological
Product number
T5006-50
Product name
Thielavin A
Packaging
500ug
Price
$582
Updated
2021/12/16
TRC
Product number
T345095
Product name
ThielavinA
Packaging
1mg
Price
$735
Updated
2021/12/16
AK Scientific
Product number
2415CB
Product name
ThielavinA
Packaging
2.5mg
Price
$1660
Updated
2021/12/16
More
Less

thielavin A Chemical Properties,Usage,Production

Description

Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 (PGH2; ) and the conversion of PGH2 to PGE2 (; IC50s = 10 and 40 μM, respectively). Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

Uses

The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related thielavin B is a telomerase and cell wall transglycosylation inhibitor.

Uses

Thielavin A acts as an inhibitor of prostagladins biosynthesis.

thielavin A Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

thielavin A Suppliers

China 24 United Kingdom 1 United States 5 Global 30
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
Email
info@scrbio.com
Country
China
ProdList
10329
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12005
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Beijing Sizhengbai Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
marketing@4abio.com
Country
CHINA
ProdList
6401
Advantage
58
Beijing Taize Jiaye Technology Development Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6050
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6158
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Shanghai Bosheng Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1310057982@qq.com
Country
CHINA
ProdList
790
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6835
Advantage
58
Beijing Lebo Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6057
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6629
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6151
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58

71950-66-8, thielavin ARelated Search:

thielocin B3 PS 990 GYROPHORIC ACID EVERNIC ACID 4-BENZYLOXY-3,5-DIMETHYLBENZALDEHYDE 4-Benzyloxy-3,5-dimethylbenzoic acid thielavin A thielavin B CHEMBRDG-BB 9070990 2,5-dimethylphenyl 4-methoxybenzoate CHEMBRDG-BB 9072034

  • thielavin A
  • 4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
  • Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
  • 71950-66-8