ChemicalBook > CAS DataBase List > JACOLINE

JACOLINE

Product Name
JACOLINE
CAS No.
480-76-2
Chemical Name
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber
CB61438381
Molecular Formula
C18H27NO7
Formula Weight
369.41
MOL File
480-76-2.mol
More
Less

JACOLINE Property

Melting point:
221°C
Boiling point:
583.5±50.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
pka
12.40±0.60(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
J210403
Product name
Jacoline
Packaging
2.5mg
Price
$2640
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
1mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
2mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001950
Product name
JACOLINE
Purity
95.00%
Packaging
5MG
Price
$505.59
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
5mg
Price
$750
Updated
2021/12/16
More
Less

JACOLINE Chemical Properties,Usage,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

JACOLINE Suppliers

China 15 United Kingdom 1 United States 2 Global 18
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7057
Advantage
55
Biyu Biotechnology (Shanghai) Co., ltd
Tel
021-26018599
Country
China
ProdList
270
Advantage
56
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
10002
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58

480-76-2, JACOLINERelated Search:

retronecine 3-BUTOXYPYRROLIDINE (2S)-2,3-Dihydroxy-2-methyl-propanoic Acid Methyl Ester 90% (R)-ETHYL 3-METHYL-2-HYDROXYBUTANOATE 2,3,5,7A-TETRAHYDRO-1H-PYRROLIZINE (S)-ALLYL LACTATE JACOLINE DL-LEUCIC ACID ISOPROPYL ESTER 3-PROPOXYPYRROLIDINE

  • JACOLINE
  • Jacolin
  • [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
  • (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione
  • 480-76-2