3-Hydroxy-2-nitropyridine
- Product Name
- 3-Hydroxy-2-nitropyridine
- CAS No.
- 15128-82-2
- Chemical Name
- 3-Hydroxy-2-nitropyridine
- Synonyms
- 2-Nitro-pyridin-3-ol;NSC 97501;2-nitro-3-pyridino;TIMTEC-BB SBB004168;2-NITRO-3-PYRIDINOL;3-Hydroxy-2-nitropyr;3-PYRIDINOL, 2-NITRO-;Crizotinib Impurity 8;2-nitro-3-pyridinolate;3-Hydroxy-2-Nitropyrine
- CBNumber
- CB6145215
- Molecular Formula
- C5H4N2O3
- Formula Weight
- 140.1
- MOL File
- 15128-82-2.mol
3-Hydroxy-2-nitropyridine Property
- Melting point:
- 69-71 °C (lit.)
- Boiling point:
- 256.56°C (rough estimate)
- Density
- 1.5657 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Crystalline Powder
- pka
- 0.31±0.22(Predicted)
- color
- Yellow
- BRN
- 124473
- InChIKey
- QBPDSKPWYWIHGA-UHFFFAOYSA-N
- CAS DataBase Reference
- 15128-82-2(CAS DataBase Reference)
- EPA Substance Registry System
- 3-Hydroxy-2-nitropyridine (15128-82-2)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- RTECS
- UU7715000
- Hazard Note
- Irritant
- HS Code
- 29333990
- Toxicity
- mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04089,
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 107255
- Product name
- 3-Hydroxy-2-nitropyridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $49.6
- Updated
- 2023/06/20
- Product number
- 107255
- Product name
- 3-Hydroxy-2-nitropyridine
- Purity
- 97%
- Packaging
- 100g
- Price
- $188
- Updated
- 2023/06/20
- Product number
- H0764
- Product name
- 3-Hydroxy-2-nitropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $150
- Updated
- 2024/03/01
- Product number
- A14887
- Product name
- 3-Hydroxy-2-nitropyridine, 98%
- Packaging
- 10g
- Price
- $39.65
- Updated
- 2024/03/01
- Product number
- A14887
- Product name
- 3-Hydroxy-2-nitropyridine, 98%
- Packaging
- 50g
- Price
- $129.65
- Updated
- 2024/03/01
3-Hydroxy-2-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization.
Preparation
Synthesis of 3-hydroxy-2-nitropyridine: add 10g of 3-hydroxypyridine, 80ml of ethyl acetate, 4.2g of KNO3 and 21ml of acetic anhydride into a 250mL three-necked flask, and heat at 45°C with magnetic stirring After the reaction is completed, it is cooled to room temperature, filtered with suction, washed with a small amount of ethyl acetate for 1 to 2 times, the filtrate is taken to adjust the pH to neutrality with saturated NaOH solution, and extracted with ethyl acetate for 3 to 4 times. , take the extract and add activated carbon and heat under reflux for 1 hour, cool and filter, take the filtrate, dry with anhydrous magnesium sulfate, filter, concentrate on a rotary evaporator, and dry in a drying oven. 11.9 g of 3-hydroxy-2-nitropyridine was obtained with a yield of 81%.
3-Hydroxy-2-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Hydroxy-2-nitropyridine manufacturers
- Product
- 2-Nitro-3-pyridinol 15128-82-2
- Price
- US $60.00-50.00/box
- Min. Order
- 1box
- Purity
- 99.99%
- Supply Ability
- 500 box
- Release date
- 2024-05-14
- Product
- 2-Nitro-3-pyridinol 15128-82-2
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 3-Hydroxy-2-nitropyridine 15128-82-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08