5-Chloro-2-hydroxy-3-nitropyridine
- Product Name
- 5-Chloro-2-hydroxy-3-nitropyridine
- CAS No.
- 21427-61-2
- Chemical Name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Synonyms
- 5-Chlo;NSC 64258;5-Chloro-3-nitro-2-pyridone;5-CHLORO-3-NITRO-2-PYRIDINOL;5-CHLORO-3-NITROPYRIDIN-2-OL;oro-2-hydroxy-3-nitropyridine;5-chloro-3-nitro-1H-pyridin-2-one;5-Chloro-3-nitro-2(1H)-pyridinone;5-chloro-3-nitropyridin-2(1H)-one;5-Chloro-3-nitropyridin-2-ol, 95+%
- CBNumber
- CB2479170
- Molecular Formula
- C5H3ClN2O3
- Formula Weight
- 174.54
- MOL File
- 21427-61-2.mol
5-Chloro-2-hydroxy-3-nitropyridine Property
- Melting point:
- 232-236 °C
- Boiling point:
- 284.1±40.0 °C(Predicted)
- Density
- 1.61±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Dimethylformamide
- form
- powder to crystal
- pka
- 6.31±0.10(Predicted)
- color
- Light yellow to Yellow to Green
- BRN
- 383852
- CAS DataBase Reference
- 21427-61-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 26-36/37/39-39-36-37
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29337900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 679747
- Product name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $124
- Updated
- 2023/01/07
- Product number
- C1972
- Product name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $136
- Updated
- 2025/07/31
- Product number
- C1972
- Product name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $404
- Updated
- 2025/07/31
- Product number
- C366650
- Product name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Packaging
- 5g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- C5010-30
- Product name
- 5-Chloro-2-hydroxy-3-nitropyridine
- Packaging
- 10g
- Price
- $425
- Updated
- 2021/12/16
5-Chloro-2-hydroxy-3-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
White to light brown solid
Uses
5-Chloro-2-hydroxy-3-nitropyridine (cas# 21427-61-2) is a compound useful in organic synthesis.
Synthesis
1072-98-6
21427-61-2
Preparation of Example A2 5-chloro-2-hydroxy-3-nitropyridine (STR9): 321 g of 2-amino-5-chloropyridine was slowly added dropwise to 1.25 L of concentrated sulfuric acid with continuous stirring until the raw material was completely dissolved. Subsequently, 172.5 g of sodium nitrite (dissolved in 240 mL of water) was slowly added at 40°C to 45°C and the reaction mixture continued to be stirred for 15 minutes. Next, 125 mL of pure nitric acid was slowly added dropwise over 40 minutes at 50°C. The reaction mixture was maintained at 55°C for 1 hour and then the reaction was quenched by pouring into 5 kg of ice water. The yellow precipitated product was collected by filtration, washed thoroughly with deionized water and dried at 60°C to afford 351 g of 5-chloro-2-hydroxy-3-nitropyridine in 80.5% of the theoretical yield and a melting point of 229°C to 231°C.
References
[1] Patent: US5274100, 1993, A
[2] Yakugaku Zasshi, 1952, vol. 72, p. 431
[3] Chem.Abstr., 1953, p. 6404
5-Chloro-2-hydroxy-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-2-hydroxy-3-nitropyridine manufacturers
- Product
- 5-Chloro-2-hydroxy-3-nitropyridine 21427-61-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 5-Chloro-2-hydroxy-3-nitropyridine 21427-61-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13
- Product
- 5-Chloro-2-hydroxy-3-nitropyridine 21427-61-2
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08