ChemicalBook > CAS DataBase List > 3-Hydroxy-2-nitropyridine

3-Hydroxy-2-nitropyridine

Product Name
3-Hydroxy-2-nitropyridine
CAS No.
15128-82-2
Chemical Name
3-Hydroxy-2-nitropyridine
Synonyms
2-Nitro-pyridin-3-ol;NSC 97501;2-nitro-3-pyridino;TIMTEC-BB SBB004168;2-NITRO-3-PYRIDINOL;3-Hydroxy-2-nitropyr;3-PYRIDINOL, 2-NITRO-;Crizotinib Impurity 8;2-nitro-3-pyridinolate;3-Hydroxy-2-Nitropyrine
CBNumber
CB6145215
Molecular Formula
C5H4N2O3
Formula Weight
140.1
MOL File
15128-82-2.mol
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3-Hydroxy-2-nitropyridine Property

Melting point:
69-71 °C (lit.)
Boiling point:
256.56°C (rough estimate)
Density 
1.5657 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Crystalline Powder
pka
0.31±0.22(Predicted)
color 
Yellow
BRN 
124473
InChIKey
QBPDSKPWYWIHGA-UHFFFAOYSA-N
CAS DataBase Reference
15128-82-2(CAS DataBase Reference)
EPA Substance Registry System
3-Hydroxy-2-nitropyridine (15128-82-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
UU7715000
Hazard Note 
Irritant
HS Code 
29333990
Toxicity
mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04089,
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
107255
Product name
3-Hydroxy-2-nitropyridine
Purity
97%
Packaging
25g
Price
$49.6
Updated
2023/06/20
Sigma-Aldrich
Product number
107255
Product name
3-Hydroxy-2-nitropyridine
Purity
97%
Packaging
100g
Price
$188
Updated
2023/06/20
TCI Chemical
Product number
H0764
Product name
3-Hydroxy-2-nitropyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$150
Updated
2024/03/01
Alfa Aesar
Product number
A14887
Product name
3-Hydroxy-2-nitropyridine, 98%
Packaging
10g
Price
$39.65
Updated
2024/03/01
Alfa Aesar
Product number
A14887
Product name
3-Hydroxy-2-nitropyridine, 98%
Packaging
50g
Price
$129.65
Updated
2024/03/01
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3-Hydroxy-2-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization.

Preparation

Synthesis of 3-hydroxy-2-nitropyridine: add 10g of 3-hydroxypyridine, 80ml of ethyl acetate, 4.2g of KNO3 and 21ml of acetic anhydride into a 250mL three-necked flask, and heat at 45°C with magnetic stirring After the reaction is completed, it is cooled to room temperature, filtered with suction, washed with a small amount of ethyl acetate for 1 to 2 times, the filtrate is taken to adjust the pH to neutrality with saturated NaOH solution, and extracted with ethyl acetate for 3 to 4 times. , take the extract and add activated carbon and heat under reflux for 1 hour, cool and filter, take the filtrate, dry with anhydrous magnesium sulfate, filter, concentrate on a rotary evaporator, and dry in a drying oven. 11.9 g of 3-hydroxy-2-nitropyridine was obtained with a yield of 81%.

3-Hydroxy-2-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxy-2-nitropyridine Suppliers

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View Lastest Price from 3-Hydroxy-2-nitropyridine manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
2-Nitro-3-pyridinol 15128-82-2
Price
US $60.00-50.00/box
Min. Order
1box
Purity
99.99%
Supply Ability
500 box
Release date
2024-05-14
Hebei Chuanghai Biotechnology Co,.LTD
Product
3-Hydroxy-2-nitropyridine 15128-82-2
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-15
Henan Fengda Chemical Co., Ltd
Product
2-Nitro-3-pyridinol 15128-82-2
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30

15128-82-2, 3-Hydroxy-2-nitropyridineRelated Search:

3-Aminopyridine 3-Hydroxy-2-methylpyridine 2-NITROPYRIDINE 3-Hydroxypyridine CHLOROPHOSPHONAZO III 3-Hydroxy-2-pyrrolidinone 3-HYDROXY-1,5-NAPHTHYRIDINE Nitromethane NITROGEN DIOXIDE 2,4,6-Trinitrotoluene Nitrobenzene TRITON 3-Bromo-6-hydroxy -5-nitropyridine,5-Bromo-3-nitro-2-pyridinol, 5-Bromo-2-hydroxy-3-nitropyridine,5-BROMO-2-HYDROXY-3-NITROPYRIDINE 2-HYDROXY-4-NITROPYRIDINE,2-HYDROXY-4-NITROPYRIDINE 97%,2-Hydroxy-4-nitropyridine97% 5-Chloro-2-hydroxy-3-nitropyridine 95+%,5-CHLORO-2-HYDROXY-3-NITROPYRIDINE 4-Hydroxy-2-nitropyridine97%,4-HYDROXY-2-NITROPYRIDINE,4-HYDROXY-2-NITROPYRIDINE 97% 3-CHLORO-2-HYDROXY-5-NITROPYRIDINE 2-Bromo-6-hydroxy-3-nitropyridine

  • 2-nitro-3-pyridino
  • 2-Nitro-pyridin-3-ol
  • 3-HYDROXY-2-NITROPYRIDINE
  • 3-PYRIDINOL, 2-NITRO-
  • 2-NITRO-3-PYRIDINOL
  • 3-Hydroxy-2-Nitro Pyridine 2-Nitro-3-Hydroxy Pyridine
  • 3-HYDROXY-2-NITROPYRIDINE 97%
  • TIMTEC-BB SBB004168
  • 2-nitro-3-pyridinolate
  • Crizotinib Impurity 8
  • 3-Hydroxy-2-Nitropyrine
  • 2-NITRO-3-HYDROPYRIDINE
  • 3-Pyridinol,2-nitro-(6CI,8CI,9CI)
  • 3-HYDROXY-2-NITROPYRIDINE 98+%
  • 3-Hydroxy-2-nitropyridine,97%
  • 3-Hydroxy-2-nitropyr
  • 3-Hydroxy-2-nitropyridine, 97% 100GR
  • 3-Hydroxy-2-nitropyridine, 97% 25GR
  • NSC 97501
  • 3-Hydroxy-2-nitropyridine&gt
  • 3-Hydroxy-2-nitropyridine ISO 9001：2015 REACH
  • 15128-82-2
  • 15128-82-0
  • 15128-37-6
  • C5H4N2O3
  • Building Blocks
  • C5
  • Heterocyclic Building Blocks
  • Pyridines
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Pyridine
  • Pyridines derivates
  • CHIRAL CHEMICALS
  • NITRO
  • blocks
  • NitroCompounds
  • Pyridines
  • Heterocycles
  • 15128-82-2