IEM 1460

Product Name: IEM 1460
CAS No.: 121034-89-7
Chemical Name: IEM 1460
Synonyms: IEM 1460;5-(1-adamantylmethylamino)pentyl-trimethylazanium:bromide:hydrobromide;N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromidehydrobromide;N,N,N-TRIMETHYL-5-[(TRICYCLO[3.3.1.13,7]DEC-1-YLMETHYL)AMINO]-1-PENTANAMINIUMBROMIDE HYDROBROMIDE
CBNumber: CB6148913
Molecular Formula: C19H38Br2N2
Formula Weight: 454.34
MOL File: 121034-89-7.mol

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IEM 1460 Property

storage temp.: Desiccate at RT
solubility: Soluble to 100 mM in water and to 100 mM in DMSO
form: solid
color: white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15623
Product name: IEM 1460
Purity: ≥98%
Packaging: 10mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 15623
Product name: IEM 1460
Purity: ≥98%
Packaging: 50mg
Price: $388
Updated: 2024/03/01

Tocris

Product number: 1636
Product name: IEM1460
Purity: ≥98%(HPLC)
Packaging: 50
Price: $526
Updated: 2021/12/16

Tocris

Product number: 1636
Product name: IEM1460
Purity: ≥98%(HPLC)
Packaging: 10
Price: $125
Updated: 2021/12/16

TRC

Product number: I942010
Product name: IEM1460
Packaging: 10mg
Price: $275
Updated: 2021/12/16

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IEM 1460 Chemical Properties,Usage,Production

Description

IEM 1460 is an adamantine derivative that blocks both AMPA- and NMDA-type glutamate receptor (GluR) channels (IC₅₀ = 10 μM-0.1 mM). It is selective for Ca²⁺-permeable GluR channels, which lack the GluR2 R subunit, and has been used to identify Ca²⁺-permeable glutamate receptors in the brain.

Uses

IEM 1460 is an Adamantane derivative and open-channel blocker of AMPA currents.

Biological Activity

Voltage-dependent open-channel blocker of AMPA receptors. Displays selectivity between subtypes, blocking GluR2 subunit-lacking (Ca 2+ -permeable) receptors more potently than GluR2-containing receptors (IC 50 values are 2.6 and 1102 μ M respectively). Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo .

storage

Room temperature (desiccate)

IEM 1460 Preparation Products And Raw materials

Raw materials

Preparation Products

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IEM 1460 Suppliers

CHINA 32 Germany 2 Switzerland 1 United Kingdom 1 United States 8 USA 1 Global 45

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44808
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 13774214275
Email: gaojun@univ-bio.com
Country: China
ProdList: 24990
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24648
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 4869
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

121034-89-7, IEM 1460Related Search:

IEM-1460 DIBROMIDE IEM 1460

IEM 1460

N,N,N-TRIMETHYL-5-[(TRICYCLO[3.3.1.13,7]DEC-1-YLMETHYL)AMINO]-1-PENTANAMINIUMBROMIDE HYDROBROMIDE

N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromidehydrobromide

5-(1-adamantylmethylamino)pentyl-trimethylazanium:bromide:hydrobromide

121034-89-7

C19H37N2BrHBr

Selective inhibitor of a subtype of AMPA receptors (Ca2+ permeable, lacking GluR2 subunits); tool for functionally discriminating between AMPA receptors of different subunit composition

Ligand-Gated Ion Channels

Ion Channels

Ionotropic Glutamate Receptor Modulators

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Glutamate receptor