(4-BENZOYL-PHENOXY)-ACETIC ACID
- Product Name
- (4-BENZOYL-PHENOXY)-ACETIC ACID
- CAS No.
- 6322-83-4
- Chemical Name
- (4-BENZOYL-PHENOXY)-ACETIC ACID
- Synonyms
- 105380;2-(4-benzoylphenoxy)acetic acid;Acetic acid, (4-benzoylphenoxy)-;Acetic acid, 2-(4-benzoylphenoxy)-
- CBNumber
- CB61491229
- Molecular Formula
- C15H12O4
- Formula Weight
- 256.25
- MOL File
- 6322-83-4.mol
(4-BENZOYL-PHENOXY)-ACETIC ACID Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B208653
- Product name
- (4-Benzoyl-phenoxy)-aceticacid
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B208653
- Product name
- (4-Benzoyl-phenoxy)-aceticacid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B208653
- Product name
- (4-Benzoyl-phenoxy)-aceticacid
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AK343590
- Product name
- 2-(4-Benzoylphenoxy)aceticacid
- Purity
- 97%
- Packaging
- 100mg
- Price
- $13
- Updated
- 2021/12/16
- Product number
- AK343590
- Product name
- 2-(4-Benzoylphenoxy)aceticacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $46
- Updated
- 2021/12/16
(4-BENZOYL-PHENOXY)-ACETIC ACID Chemical Properties,Usage,Production
Synthesis
51848-56-7
6322-83-4
General procedure for the synthesis of (4-benzoylphenoxy)-acetic acid from ethyl 2-(4-benzoylphenoxy)acetate: 1N NaOH solution (3.9 mmol) was added to an ethanol (20 mL) solution of ethyl 2-(4-benzoylphenoxy)acetate (3.0 mmol) and the reaction mixture was stirred for 10-15 h at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was dissolved in water (20 mL) and acidified with concentrated HCl at 0 °C. Subsequently, the aqueous layer was extracted with dichloromethane (3 x 20 mL), the organic layers were combined and dried with anhydrous Na2SO4. After drying, the organic layer was concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by crystallization from cyclohexane or chloroform to afford the target compound (4-benzoylphenoxy)-acetic acid in good yield.
References
[1] Medicinal Chemistry, 2014, vol. 10, # 1, p. 59 - 65
[2] Anales de la Real Sociedad Espanola de Fisica y Quimica, vol. 24, p. 88
[3] Chem. Zentralbl., 1926, vol. 97, # II, p. 21
[4] Tetrahedron Letters, 2004, vol. 45, # 10, p. 2239 - 2241
[5] Journal of Peptide Science, 2010, vol. 16, # 10, p. 551 - 557
(4-BENZOYL-PHENOXY)-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(4-BENZOYL-PHENOXY)-ACETIC ACID Suppliers
- Tel
- --
- Fax
- --
- enamine@enamine.net
- Country
- Ukraine
- ProdList
- 6216
- Advantage
- 67
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38