3-((benzyloxy)methyl)cyclobutanone
Application- Product Name
- 3-((benzyloxy)methyl)cyclobutanone
- CAS No.
- 172324-67-3
- Chemical Name
- 3-((benzyloxy)methyl)cyclobutanone
- Synonyms
- 3-((benzyloxy)methyl)cyclobutanone;3-(Benzyloxymethyl)cyclobutanone,97%;3-[(benzyloxy)methyl]cyclobutan-1-one;3-[(Phenylmethoxy)methyl]cyclobutanone;3-(phenylmethoxymethyl)cyclobutan-1-one;3-(Benzyloxymethyl)cyclobutanone - B11865;Cyclobutanone, 3-[(phenylMethoxy)Methyl]-;2-Naphthalenesulfonylchloride,5,6,7,8-tetrahydro-5,5,8,9-tetramethyl-
- CBNumber
- CB61558245
- Molecular Formula
- C12H14O2
- Formula Weight
- 190.24
- MOL File
- 172324-67-3.mol
3-((benzyloxy)methyl)cyclobutanone Property
- Boiling point:
- 295.1±13.0 °C(Predicted)
- Density
- 1.105±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2914500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B130115
- Product name
- 3-((Benzyloxy)methyl)cyclobutanone
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB31314
- Product name
- 3-[(Benzyloxy)methyl]cyclobutanone
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB31314
- Product name
- 3-[(Benzyloxy)methyl]cyclobutanone
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB31314
- Product name
- 3-[(Benzyloxy)methyl]cyclobutanone
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FB31314
- Product name
- 3-[(Benzyloxy)methyl]cyclobutanone
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
3-((benzyloxy)methyl)cyclobutanone Chemical Properties,Usage,Production
Application
3-(benzyloxymethyl)cyclobutanone can be used as a pharmaceutical intermediate in the synthesis of other compounds with certain activities. Examples of its applications are as follows: It can be used to prepare cis-3-[(benzyloxymethyl)cyclobutanol]: At -70°C, with stirring in tetrahydrofuran, a 1M solution of trisec-butylborohydride in tetrahydrofuran (40 ml) is added dropwise to a solution of 3-(benzyloxymethyl)cyclobutanone (1.166 g, 6.13 mmol), maintaining the reaction temperature below -65°C. The reaction is then heated to room temperature over 18 hours. The reaction mixture is quenched with a saturated aqueous sodium bicarbonate solution (25 ml) and then cooled to 5°C. A 30% aqueous hydrogen peroxide solution (4 ml) is added dropwise, maintaining the reaction temperature below 10°C. The mixture is extracted from water into ethyl acetate (50 ml), and the combined organic phases are washed with brine (30 ml), dried with magnesium sulfate, filtered, and evaporated under vacuum. The crude substance was purified by silica gel column chromatography and eluted with 25-50% ethyl acetate:pentane to give a colorless oil.
3-((benzyloxy)methyl)cyclobutanone Preparation Products And Raw materials
Raw materials
Preparation Products
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