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3-((benzyloxy)methyl)cyclobutanone

Application
Product Name
3-((benzyloxy)methyl)cyclobutanone
CAS No.
172324-67-3
Chemical Name
3-((benzyloxy)methyl)cyclobutanone
Synonyms
3-((benzyloxy)methyl)cyclobutanone;3-(Benzyloxymethyl)cyclobutanone,97%;3-[(benzyloxy)methyl]cyclobutan-1-one;3-[(Phenylmethoxy)methyl]cyclobutanone;3-(phenylmethoxymethyl)cyclobutan-1-one;3-(Benzyloxymethyl)cyclobutanone - B11865;Cyclobutanone, 3-[(phenylMethoxy)Methyl]-;2-Naphthalenesulfonylchloride,5,6,7,8-tetrahydro-5,5,8,9-tetramethyl-
CBNumber
CB61558245
Molecular Formula
C12H14O2
Formula Weight
190.24
MOL File
172324-67-3.mol
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3-((benzyloxy)methyl)cyclobutanone Property

Boiling point:
295.1±13.0 °C(Predicted)
Density 
1.105±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Appearance
Colorless to light yellow Liquid
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Safety

HS Code 
2914500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
B130115
Product name
3-((Benzyloxy)methyl)cyclobutanone
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB31314
Product name
3-[(Benzyloxy)methyl]cyclobutanone
Packaging
250mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB31314
Product name
3-[(Benzyloxy)methyl]cyclobutanone
Packaging
500mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB31314
Product name
3-[(Benzyloxy)methyl]cyclobutanone
Packaging
1g
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB31314
Product name
3-[(Benzyloxy)methyl]cyclobutanone
Packaging
2g
Price
$200
Updated
2021/12/16
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3-((benzyloxy)methyl)cyclobutanone Chemical Properties,Usage,Production

Application

3-(benzyloxymethyl)cyclobutanone can be used as a pharmaceutical intermediate in the synthesis of other compounds with certain activities. Examples of its applications are as follows: It can be used to prepare cis-3-[(benzyloxymethyl)cyclobutanol]: At -70°C, with stirring in tetrahydrofuran, a 1M solution of trisec-butylborohydride in tetrahydrofuran (40 ml) is added dropwise to a solution of 3-(benzyloxymethyl)cyclobutanone (1.166 g, 6.13 mmol), maintaining the reaction temperature below -65°C. The reaction is then heated to room temperature over 18 hours. The reaction mixture is quenched with a saturated aqueous sodium bicarbonate solution (25 ml) and then cooled to 5°C. A 30% aqueous hydrogen peroxide solution (4 ml) is added dropwise, maintaining the reaction temperature below 10°C. The mixture is extracted from water into ethyl acetate (50 ml), and the combined organic phases are washed with brine (30 ml), dried with magnesium sulfate, filtered, and evaporated under vacuum. The crude substance was purified by silica gel column chromatography and eluted with 25-50% ethyl acetate:pentane to give a colorless oil.

3-((benzyloxy)methyl)cyclobutanone Preparation Products And Raw materials

Raw materials

Preparation Products

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3-((benzyloxy)methyl)cyclobutanone Suppliers

Alfa Aesar
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021-67582001/03/05
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Energy Chemical
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172324-67-3, 3-((benzyloxy)methyl)cyclobutanoneRelated Search:


  • Cyclobutanone, 3-[(phenylMethoxy)Methyl]-
  • 3-[(Phenylmethoxy)methyl]cyclobutanone
  • 3-[(benzyloxy)methyl]cyclobutan-1-one
  • 3-(Benzyloxymethyl)cyclobutanone - B11865
  • 3-((benzyloxy)methyl)cyclobutanone
  • 3-(phenylmethoxymethyl)cyclobutan-1-one
  • 3-(Benzyloxymethyl)cyclobutanone,97%
  • 2-Naphthalenesulfonylchloride,5,6,7,8-tetrahydro-5,5,8,9-tetramethyl-
  • 172324-67-3