2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine

Uses

Product Name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
CAS No.: 35265-83-9
Chemical Name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Synonyms: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine;2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine-3;Thieno[3,2-d]pyriMidine, 2,4-dichloro-7-Methyl-;2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine ISO 9001：2015 REACH
CBNumber: CB61563632
Molecular Formula: C7H4Cl2N2S
Formula Weight: 219.09
MOL File: 35265-83-9.mol

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2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine Property

Boiling point:: 293℃
Density: 1.568
Flash point:: 131℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.48±0.40(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C7H4Cl2N2S/c1-3-2-12-5-4(3)10-7(9)11-6(5)8/h2H,1H3
InChIKey: WUXYWALKGQDXFI-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(Cl)=C2SC=C(C)C2=N1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D437250
Product name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142021
Product name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Packaging: 250mg
Price: $72.5
Updated: 2021/12/16

AK Scientific

Product number: W5692
Product name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Packaging: 250mg
Price: $115
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142021
Product name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142021
Product name: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine
Packaging: 1g
Price: $218.75
Updated: 2021/12/16

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2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine Chemical Properties,Usage,Production

Uses

2,4-Dichloro-7-methylthiopheno[3,2-D]pyrimidine is a heterocyclic derivative that can be used as an intermediate in organic synthesis.

Synthesis

35265-81-7

35265-83-9

GENERAL STEPS: 7-methylthieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (89.4 g) was added to a solution of acetonitrile (450 mL) containing phosphorochloridic acid (312 g, 2.04 mol), and N,N-dimethylaniline (44.6 g, 0.368 mol) over 10 minutes. The reaction mixture was heated to 85°C and stirred at this temperature for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and then slowly poured into a mixture of ice (900 g) and water (300 mL) while controlling the temperature below 10°C. Stirring was continued at this temperature for 30 minutes. The resulting solid product was collected by filtration, washed with water (450 mL) and subsequently dried under reduced pressure at 50 °C for 24 h to afford the target compound 2,4-dichloro-7-methylthieno[3,2-d]pyrimidine (97.0 g, 90% yield). The product was a white solid and its structure was confirmed by 1H NMR (400 MHz, CDCl3) δ 7.75 (s, 1H), 2.50 (s, 3H) and LCMS (ESI pos) m/z [M+H] 220.

References

[1] Patent: US2014/100366, 2014, A1. Location in patent: Page/Page column
[2] Patent: WO2008/58285, 2008, A2. Location in patent: Page/Page column 51
[3] Patent: US2001/6969, 2001, A1
[4] Patent: US6339089, 2002, B2. Location in patent: Referential example 17
[5] European Journal of Medicinal Chemistry, 2011, vol. 46, # 1, p. 71 - 76

2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine Suppliers

Canada 1 China 78 Germany 1 India 2 Switzerland 1 United Kingdom 3 United States 9 Global 95

Hangzhou Sulfuchem Material Technology Co., Ltd.

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View Lastest Price from 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine 35265-83-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-25

Career Henan Chemical Co

Product: 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine 35265-83-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

35265-83-9, 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidineRelated Search:

4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE 2,4-Dichlorothieno[3,2-d]pyrimidine 2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine

2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine

Thieno[3,2-d]pyriMidine, 2,4-dichloro-7-Methyl-

2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine-3

2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine ISO 9001：2015 REACH

35265-83-9

Heterocycle-Pyrimidine series