ChemicalBook > CAS DataBase List > Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%

Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%

Product Name
Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
CAS No.
3998-88-7
Chemical Name
Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
Synonyms
Ethyl 2-chloro-6-methyl-4-pyridinecarboxylate;2-Chloro-6-methylisonicotinic Acid Ethyl Ester;Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%;Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%;2-Chloro-6-methylpyridine-4-carboxylic acid ethyl ester;4-Pyridinecarboxylic acid, 2-chloro-6-Methyl-, ethyl ester;JR-14076, Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
CBNumber
CB61569634
Molecular Formula
C9H10ClNO2
Formula Weight
199.63
MOL File
3998-88-7.mol
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Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% Property

Melting point:
65-67°C
Boiling point:
107°C/1.5mm
Density 
1?+-.0.06 g/cm3(Predicted)
Flash point:
107°C/1.5mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
-0.14±0.10(Predicted)
color 
White to Almost white
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
JRD0891
Product name
Ethyl 2-chloro-6-methylpyridine-4-carboxylate
Packaging
1G
Price
$107
Updated
2025/07/31
TCI Chemical
Product number
E1262
Product name
Ethyl 2-Chloro-6-methylisonicotinate
Purity
>98.0%(GC)
Packaging
1g
Price
$46
Updated
2025/07/31
TCI Chemical
Product number
E1262
Product name
Ethyl 2-Chloro-6-methylisonicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$137
Updated
2025/07/31
TRC
Product number
E903788
Product name
Ethyl2-Chloro-6-methylpyridine-4-carboxylate
Packaging
500mg
Price
$90
Updated
2021/12/16
Apolloscientific
Product number
OR952499
Product name
Ethyl2-chloro-6-methylpyridine-4-carboxylate
Purity
95%
Packaging
1g
Price
$105
Updated
2021/12/16
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Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% Chemical Properties,Usage,Production

Synthesis

25462-85-5

64-17-5

3998-88-7

Step 1: Synthesis of ethyl 2-chloro-6-methylisonicotinate (97). Concentrated sulfuric acid (2 mL) was added dropwise to a stirred solution of 2-chloro-6-methylpyridine-4-carboxylic acid (7.0 g, 40.79 mmol) in ethanol (70 mL) at 0 °C. Subsequently, the reaction mixture was heated to 80 °C and kept for 12 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under vacuum to remove the solvent. The concentrated residue was diluted with ethyl acetate and washed sequentially with water, sodium bicarbonate solution and saturated aqueous sodium chloride solution. The organic layer was separated, dried over anhydrous sodium sulfate, filtered and concentrated to give ethyl 2-chloro-6-methylisonicotinate (97) (7 g, 86% yield) as a white solid.

References

[1] Patent: US2010/249071, 2010, A1. Location in patent: Page/Page column 63-64
[2] Patent: WO2008/29371, 2008, A1. Location in patent: Page/Page column 41
[3] Patent: WO2009/24905, 2009, A1. Location in patent: Page/Page column 38-39; 49
[4] Patent: US2010/63108, 2010, A1. Location in patent: Page/Page column 16
[5] Patent: US2011/46170, 2011, A1. Location in patent: Page/Page column 17

Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% Suppliers

Alfa Aesar
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View Lastest Price from Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl 2-chloro-6-methylpyridine-4-carboxylate 3998-88-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-14
Career Henan Chemical Co
Product
Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97% 3998-88-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-03

3998-88-7, Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%Related Search:


  • Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
  • 4-Pyridinecarboxylic acid, 2-chloro-6-Methyl-, ethyl ester
  • 2-Chloro-6-methylpyridine-4-carboxylic acid ethyl ester
  • JR-14076, Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
  • 2-Chloro-6-methylisonicotinic Acid Ethyl Ester
  • Ethyl 2-chloro-6-methyl-4-pyridinecarboxylate
  • Ethyl 2-chloro-6-methylpyridine-4-carboxylate, 97%
  • 3998-88-7