ChemicalBook > CAS DataBase List > N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE

Product Name
N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
CAS No.
80376-66-5
Chemical Name
N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
Synonyms
meyers' tms form;N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE;N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine,98%;N'-tert-butyl-N-methyl-N-(trimethylsilylmethyl)methanimidamide;Methanimidamide, N'-(1,1-dimethylethyl)-N-methyl-N-[(trimethylsilyl)methyl]-;N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidineMeyers' TMS form reagent
CBNumber
CB6160140
Molecular Formula
C10H24N2Si
Formula Weight
200.4
MOL File
80376-66-5.mol
More
Less

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Property

Boiling point:
78-80 °C (7 mmHg)
refractive index 
1.45-1.452
storage temp. 
0-6°C
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Chemical Properties,Usage,Production

Chemical Properties

CLEAR PALE YELLOW LIQUID

Uses

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE conveniently effects the transformation of ketones and aldehydes to homologated nitriles, amines, aldehydes, and ketones.

Synthesis

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE is easily synthesized by a two-step procedure (eq 1).1 Initially, the condensation of t-Butylamine with either N,N-Dimethylformamide or dimethylformamide dimethyl acetal cleanly affords N′-t-Butyl-N,N-dimethylformamidine. Subsequent lithiation and silylation with Chlorotrimethylsilane results in a 70% overall yield of the purified title reagent.

storage

The reagent should be handled in a fume hood. Refrigeration should be used for prolonged storage.

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Suppliers

Belgium 1 Germany 1 Japan 1 United States 1 Global 4
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74

80376-66-5, N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINERelated Search:

(Trimethylsilyl)methylamine N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE N'-TERT-BUTYL-N,N-DIMETHYLFORMAMIDINE

  • meyers' tms form
  • N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine,98%
  • N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidineMeyers' TMS form reagent
  • N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
  • Methanimidamide, N'-(1,1-dimethylethyl)-N-methyl-N-[(trimethylsilyl)methyl]-
  • N'-tert-butyl-N-methyl-N-(trimethylsilylmethyl)methanimidamide
  • 80376-66-5
  • C10H24N2Si