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4-BENZYLOXY-2-HYDROXYBENZALDEHYDE

Product Name
4-BENZYLOXY-2-HYDROXYBENZALDEHYDE
CAS No.
52085-14-0
Chemical Name
4-BENZYLOXY-2-HYDROXYBENZALDEHYDE
Synonyms
4-Benzyloxysalicylaldehyde;4-BENZYLOXY-2-HYDROXYBENZALDEHYDE;2-hydroxy-4-phenylmethoxybenzaldehyde;Benzaldehyde, 2-hydroxy-4-(phenylmethoxy)-
CBNumber
CB6170446
Molecular Formula
C14H12O3
Formula Weight
228.24
MOL File
52085-14-0.mol
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4-BENZYLOXY-2-HYDROXYBENZALDEHYDE Property

Melting point:
78-80°C
Boiling point:
165-175 °C(Press: 1 Torr)
Density 
1.238±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
7.80±0.10(Predicted)
Appearance
Light brown to brown Solid
Sensitive 
Air Sensitive
BRN 
982995
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Safety

Hazard Codes 
Xi,N
Risk Statements 
36/37/38-50-43
Safety Statements 
26-36-61-36/37
HS Code 
2912210000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS001087
Product name
4-(Benzyloxy)-2-hydroxybenzaldehyde
Purity
AldrichCPR
Packaging
250MG
Price
$73.1
Updated
2025/07/31
TCI Chemical
Product number
H1904
Product name
4-(Benzyloxy)-2-hydroxybenzaldehyde
Purity
min. 98.0 %
Packaging
1G
Price
$45
Updated
2025/07/31
TCI Chemical
Product number
H1904
Product name
4-(Benzyloxy)-2-hydroxybenzaldehyde
Purity
min. 98.0 %
Packaging
5G
Price
$135
Updated
2025/07/31
TRC
Product number
B404978
Product name
4-Benzyloxy-2-hydroxybenzaldehyde
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B404978
Product name
4-Benzyloxy-2-hydroxybenzaldehyde
Packaging
500mg
Price
$75
Updated
2021/12/16
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4-BENZYLOXY-2-HYDROXYBENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

100-39-0

95-01-2

52085-14-0

2,4-Dihydroxybenzaldehyde (3.0 g, 1.0 eq.) was dissolved in acetonitrile (220 mL), sodium bicarbonate (2.2 eq.) was added at room temperature and stirred for 45 minutes. Subsequently, benzyl bromide (1.1 eq.) was slowly added to the reaction system. The reaction mixture was heated to reflux and stirred continuously. Upon completion of the reaction, the reaction was quenched with deionized water (100 mL) and subsequently extracted with ethyl acetate (3 x 25 mL). The organic phases were combined, washed with saturated saline (2 × 15 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to remove the solvent, to afford the crude product 4-phenylmethoxy-2-hydroxybenzaldehyde 12 as a white solid, which could be used in subsequent reactions without further purification.

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 15, p. 4502 - 4510
[2] Synlett, 2011, # 11, p. 1605 - 1607
[3] Organic Process Research and Development, 2011, vol. 15, # 5, p. 1149 - 1162
[4] Tetrahedron Letters, 2013, vol. 54, # 31, p. 4121 - 4124
[5] Organic Letters, 2008, vol. 10, # 21, p. 5007 - 5010

4-BENZYLOXY-2-HYDROXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BENZYLOXY-2-HYDROXYBENZALDEHYDE Suppliers

China 73 Germany 4 India 2 The Netherlands 1 United Kingdom 4 United States 11 Global 95
UnaveraChemLab GmbH
Tel
--
Fax
--
Email
axel@unavera.de
Country
Germany
ProdList
45
Advantage
0
Aaron Chemistry GmbH
Tel
--
Fax
--
Email
sales@aaron-chemistry.de
Country
Germany
ProdList
579
Advantage
60
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 4-BENZYLOXY-2-HYDROXYBENZALDEHYDE manufacturers

Career Henan Chemical Co
Product
4-BENZYLOXY-2-HYDROXYBENZALDEHYDE 52085-14-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
200KG
Release date
2020-01-07

52085-14-0, 4-BENZYLOXY-2-HYDROXYBENZALDEHYDERelated Search:

FUMARPROTOCETRARIC ACID LECANORIC ACID GYROPHORIC ACID 4'-BENZYLOXY-2'-HYDROXY-3'-METHYLACETOPHENONE ATRANORIN 4'-BENZYLOXY-2'-METHOXY-3'-METHYLACETOPHENONE EVERNIC ACID Salicylaldehyde STICTIC ACID KS 502 LOBARIC ACID 4'-Benzyloxy-2'-hydroxyacetophenone 5-(benzyloxy)-2-hydroxybenzaldehyde 4-(Benzyloxy)-3-hydroxybenzaldehyde p-Toluenesulfonate 4-BENZYLOXY-3-HYDROXYBENZALDEHYDE PHYSODIC ACID 1-[4-(BENZYLOXY)-2-HYDROXYPHENYL]-3-(4-METHOXYPHENYL)PROP-2-EN-1-ONE 2,4-BIS(BENZYLOXY)BENZALDEHYDE

  • Benzaldehyde, 2-hydroxy-4-(phenylmethoxy)-
  • 2-hydroxy-4-phenylmethoxybenzaldehyde
  • 4-BENZYLOXY-2-HYDROXYBENZALDEHYDE
  • 4-Benzyloxysalicylaldehyde
  • 52085-14-0
  • ALDEHYDE