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Sulfathiazole sodium

Product Name
Sulfathiazole sodium
CAS No.
144-74-1
Chemical Name
Sulfathiazole sodium
Synonyms
SODIUM SULFATHIAZOLE;SULFATHIAZOLE SODIUM SALT;ST-NA;Sulfathiazole(ST);Sulfathiazole Bp98;sodiumnorsulfazole;SULFATHIAZOLESOUDIM;solublesulfathiazole;sodiumsulphathiazole;SULFATHIAZOLE SODIUM
CBNumber
CB6170572
Molecular Formula
C9H10N3NaO2S2
Formula Weight
279.31
MOL File
144-74-1.mol
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Sulfathiazole sodium Property

storage temp. 
Store at -20°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
white to off-white
BRN 
3802297
Stability:
Hygroscopic
InChI
InChI=1S/C9H9N3O2S2.Na.H/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;;/h1-6H,10H2,(H,11,12);;
InChIKey
PLYRQFRFHFKJLU-UHFFFAOYSA-N
SMILES
S(C1C=CC(N)=CC=1)(=O)(=O)NC1SC=CN=1.[NaH]
CAS DataBase Reference
144-74-1(CAS DataBase Reference)
EPA Substance Registry System
Benzenesulfonamide, 4-amino-N-2-thiazolyl-, monosodium salt (144-74-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-23
WGK Germany 
2
RTECS 
WP2450000
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S0127
Product name
Sulfathiazole sodium salt
Purity
≥99%
Packaging
100g
Price
$54.1
Updated
2022/05/15
TRC
Product number
S699108
Product name
Sulfathiazole sodium salt
Packaging
250g
Price
$120
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004287
Product name
SULPHATHIAZOLE SODIUM
Purity
95.00%
Packaging
10G
Price
$158.55
Updated
2021/12/16
AK Scientific
Product number
8167AF
Product name
Sulfathiazolesodium5H2O
Packaging
250g
Price
$185
Updated
2021/12/16
AK Scientific
Product number
8167AF
Product name
Sulfathiazolesodium5H2O
Packaging
1kg
Price
$522
Updated
2021/12/16
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Sulfathiazole sodium Chemical Properties,Usage,Production

Description

Sulfathiazole sodium salt is a short-acting sulfa drug. It was a common oral and topical antibiotic until less toxic alternatives were discovered. It is no longer used in humans. Sulfathiazole is added to the diet of laboratory animals to inhibit folate formation by gut bacteria. This ensures that the animal′s only source of available folate is from their diet. Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Uses

Sulfathiazole sodium salt is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA). It can also be used in biological study of thermotherapy and sulfonamide antibiotics deciphered Cyanobacteria and Proteobacteria microbiome in huanglongbing-affected Citrus paradise and Citrus limon.

General Description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Sulfathiazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sulfathiazole sodium manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Sulfathiazole sodium 144-74-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
2000KG
Release date
2024-03-27
Hebei Duling International Trade Co. LTD
Product
Sulfathiazole sodium 144-74-1
Price
US $1.90/Box
Min. Order
1Box
Purity
99.2%
Supply Ability
25tons
Release date
2023-03-10
Hebei Yanxi Chemical Co., Ltd.
Product
Sulfathiazole Sodium 144-74-1
Price
US $40.00-40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-10-13

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