EATON'S REAGENT Property

Boiling point:

122 °C/1 mmHg

Density 

1.5 g/mL at 25 °C

refractive index 

n20/D 1.435

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

Liquid

color 

Clear

Water Solubility 

Decomposes in water.

Sensitive 

Moisture Sensitive

InChI

InChI=1S/CH4O3S.O5P2/c1-5(2,3)4;1-6(2)5-7(3)4/h1H3,(H,2,3,4);

InChIKey

JHNLZOVBAQWGQU-UHFFFAOYSA-N

SMILES

S(=O)(=O)(O)C.P(=O)(=O)OP(=O)=O

Safety

Hazard Codes 

C

Risk Statements 

34-21/22

Safety Statements 

23-26-36/37/39-45

RIDADR 

UN 2922 8/PG 2

WGK Germany 

1

HazardClass 

8

PackingGroup 

III

HS Code 

28112900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P234Keep only in original container.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

EATON'S REAGENT Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to light yellow liquid

Uses

Eaton's Reagent is used in the synthesis fluorine-based hole-transporting material, mono and bis-chalcone derivatives via Claisen-Schmidt condensation reaction between arylaldehydes and ketones and 4-hydroxycoumarins and 4-hydroxy-2-quinolinones derivatives.

Uses

Eaton′s Reagent may be used in the synthesis of the following:

• Fluorene-based hole-transporting material.
• Mono and bis-chalcone derivatives via Claisen-Schmidt condensation reaction between arylaldehydes and ketones.
• 4-Hydroxycoumarins and 4-hydroxy-2-quinolinones derivatives.

General Description

Eaton′s Reagent contains 7.7wt% phosphorus pentoxide in methanesulfonic acid. It is commonly used as a catalyst and condensing agent.