ChemicalBook > CAS DataBase List > 4-BROMO-3-NITROBENZONITRILE

4-BROMO-3-NITROBENZONITRILE

Uses

Product Name: 4-BROMO-3-NITROBENZONITRILE
CAS No.: 89642-49-9
Chemical Name: 4-BROMO-3-NITROBENZONITRILE
Synonyms: 3-nitro-4-broMobenzonitrile;2-Bromo-5-cyanonitrobenzene;4-BROMO-3-NITROBENZONITRILE;Benzonitrile, 4-bromo-3-nitro-;4-Bromo-3-nitrobenzonitrile 97%;4-BROMO-3-NITROBENZONITRILE ISO 9001：2015 REACH
CBNumber: CB6184836
Molecular Formula: C7H3BrN2O2
Formula Weight: 227.01
MOL File: 89642-49-9.mol

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4-BROMO-3-NITROBENZONITRILE Property

Melting point:: 116-120 °C
Boiling point:: 269℃
Density: 1.81
Flash point:: 116℃
storage temp.: 2-8°C
form: powder to crystal
color: White to Light yellow to Light orange

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Safety

WGK Germany: 3
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 701246
Product name: 4-Bromo-3-nitrobenzonitrile
Purity: 97%
Packaging: 25g
Price: $127.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 701246
Product name: 4-Bromo-3-nitrobenzonitrile
Purity: 97%
Packaging: 5g
Price: $204
Updated: 2025/07/31

TCI Chemical

Product number: B4708
Product name: 4-Bromo-3-nitrobenzonitrile
Purity: >98.0%(GC)
Packaging: 1g
Price: $55
Updated: 2025/07/31

TCI Chemical

Product number: B4708
Product name: 4-Bromo-3-nitrobenzonitrile
Purity: >98.0%(GC)
Packaging: 5g
Price: $167
Updated: 2025/07/31

TRC

Product number: B697965
Product name: 4-Bromo-3-nitrobenzonitrile
Packaging: 100mg
Price: $45
Updated: 2021/12/16

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4-BROMO-3-NITROBENZONITRILE Chemical Properties,Usage,Production

Uses

4-Bromo-3-nitrobenzenenitrile is an important intermediate in organic synthesis. Because it has two second-class substituents, nitro and cyano, on its aromatic ring, as well as a bromine that can participate in the reaction, these two compounds have broad application prospects in the field of organic synthesis.

Synthesis

623-00-7

89642-49-9

General procedure for the synthesis of 4-bromo-3-nitrobenzonitrile from 4-bromobenzonitrile: To a concentrated solution of 4-bromobenzonitrile (4.0 g, 22 mmol) was added concentrated sulfuric acid (10 mL) and nitric acid (6 mL) slowly and dropwise at 0 °C. The reaction mixture was kept stirred at 0 °C for 30 min, then warmed up to room temperature and continued stirring for 2.5 h. The reaction was carried out at room temperature. Upon completion of the reaction, the mixture was slowly poured into ice water. The resulting white precipitate was collected by filtration and washed with water until the washings were neutral. The resulting solid was recrystallized twice by ethanol/water solvent mixture (1:1, 20 mL) to finally obtain 4-bromo-3-nitrobenzonitrile as a white crystalline solid (2.8 g, 56% yield). The product was identified by 1H NMR (300 MHz, DMSO-d6): δ8.54 (s, 1H), 8.06 (d, J = 8.4 Hz, 1H), 7.99 (d, J = 8.4 Hz, 1H); 13C NMR (75 MHz, DMSO-d6) δ150.4,137.4,136.6,129.6,119.6, 117.0,112.6; HPLC retention time 1.96 min (10-100% CH3CN, gradient 5 min); ESI-MS m/z 227.1 ([MH]+).

References

[1] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0673
[2] Recueil des Travaux Chimiques des Pays-Bas, 1922, vol. 41, p. 36
[3] Recueil des Travaux Chimiques des Pays-Bas, 1922, vol. 41, p. 106,107
[4] Chemische Berichte, 1916, vol. 49, p. 2224
[5] Chemische Berichte, 1890, vol. 23, p. 3442

4-BROMO-3-NITROBENZONITRILE Preparation Products And Raw materials

Raw materials

K-CATALYST Ammonium nitrate PERCHLORIC ACID Ethyl acetate 3-Bromobenzonitrile Sodium bicarbonate

Preparation Products

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View Lastest Price from 4-BROMO-3-NITROBENZONITRILE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 4-BROMO-3-NITROBENZONITRILE 89642-49-9
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Bromo-3-nitrobenzonitrile 89642-49-9
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100 tons
Release date: 2020-01-10

Career Henan Chemical Co

Product: 4-BROMO-3-NITROBENZONITRILE 89642-49-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-09-03

89642-49-9, 4-BROMO-3-NITROBENZONITRILERelated Search:

2-Bromo-6-nitrobenzoic acid 2-Nitrobenzyl bromide 4-Chloro-2-nitrobenzonitrile 4-Bromo-3-nitrobenzoic acid 2-AMINO-3-BROMO-5-NITROBENZONITRILE 4-BROMO-2-NITROBENZONITRILE 2-BROMO-5-NITROBENZONITRILE,2-Bromo-5-nitrobenzonitrile 98% 3-Bromo-5-nitrobenzonitrile 3-Bromo-2-methoxy-5-trifluoromethylpyridine 2-bromo-4-nitrobenzonitrile 4-Bromobenzonitrile 4-BROMO-3-NITROBENZONITRILE 4-BROMO-3-METHYL-5-NITROBENZONITRILE 4-Bromo-3-nitrotoluene

4-BROMO-3-NITROBENZONITRILE

2-Bromo-5-cyanonitrobenzene

3-nitro-4-broMobenzonitrile

Benzonitrile, 4-bromo-3-nitro-

4-Bromo-3-nitrobenzonitrile 97%

4-BROMO-3-NITROBENZONITRILE ISO 9001：2015 REACH

89642-49-9

C7H3BrN2O2

Building Blocks

C6 to C7

Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks

C6 to C7

Cyanides/Nitriles

Nitrogen Compounds

blocks

Bromides

Carboxes

NitroCompounds

Aromatic Nitriles