Benzoic acid, 2-amino-6-hydroxy-
Uses- Product Name
- Benzoic acid, 2-amino-6-hydroxy-
- CAS No.
- 567-62-4
- Chemical Name
- Benzoic acid, 2-amino-6-hydroxy-
- Synonyms
- 6-Aminosalicylic acid;Mesalazine Impurity 22;Mesalazine Impurity 24;6-Hydroxyanthranilic acid;2-Amino-6-hydroxybenzoic acid;Benzoic acid, 2-amino-6-hydroxy-;Benzoic acid, 2-amino-6-hydroxy- ISO 9001：2015 REACH
- CBNumber
- CB61869318
- Molecular Formula
- C7H7NO3
- Formula Weight
- 153.14
- MOL File
- 567-62-4.mol
Benzoic acid, 2-amino-6-hydroxy- Property
- Melting point:
- 148℃
- Boiling point:
- 352.2±32.0 °C(Predicted)
- Density
- 1.491
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.30±0.25(Predicted)
- form
- Solid
- color
- Light Brown to Brown
Safety
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B405790
- Product name
- 2-amino-6-hydroxybenzoicacid
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- W7041
- Product name
- 2-Amino-6-hydroxybenzoicacid
- Packaging
- 5g
- Price
- $1341
- Updated
- 2021/12/16
- Product number
- FA143654
- Product name
- 2-Amino-6-hydroxybenzoic acid
- Packaging
- 100mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FA143654
- Product name
- 2-Amino-6-hydroxybenzoic acid
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- FA143654
- Product name
- 2-Amino-6-hydroxybenzoic acid
- Packaging
- 500mg
- Price
- $370
- Updated
- 2021/12/16
Benzoic acid, 2-amino-6-hydroxy- Chemical Properties,Usage,Production
Uses
6-Hydroxy-o-aminobenzoic acid is a carboxylic acid derivative that can be used as a pharmaceutical synthesis intermediate.
Synthesis
53600-33-2
567-62-4
General procedure for the synthesis of 6-hydroxy-o-toluic acid from 2-amino-6-methoxybenzoic acid: boron tribromide (1 M in dichloromethane, 3 eq.) was slowly added dropwise to an anhydrous dichloromethane solution of 2-amino-6-methoxybenzoic acid (1 eq.) at -78 °C (dry ice/acetone bath). The reaction mixture was stirred at room temperature and under nitrogen protection for 18 hours. Upon completion of the reaction, the reaction was quenched by the addition of ethanol and methanol, followed by evaporation to remove the solvent to give a brown solid product. The product can be used in subsequent reactions without further purification. The product was a brown solid in 75% yield.
References
[1] European Journal of Medicinal Chemistry, 2014, vol. 76, p. 343 - 351
[2] Journal of Organic Chemistry, 1991, vol. 56, # 23, p. 6666 - 6671
Benzoic acid, 2-amino-6-hydroxy- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Benzoic acid, 2-amino-6-hydroxy- manufacturers
- Product
- 2-amino-6-hydroxybenzoic acid 567-62-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- Benzoic acid, 2-amino-6-hydroxy- 567-62-4
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-07