Trimethoprim-d3
- Product Name
- Trimethoprim-d3
- CAS No.
- 1189923-38-3
- Chemical Name
- Trimethoprim-d3
- Synonyms
- Tiempe-d3;Uretrim-d3;Trimanyl-d3;Monotrim-d3;Instalac-d3;Syraprim-d3;Proloprim-d3;Wellcoprim-d3;Trimethoprim-d3;[2H3]-Trimethoprim
- CBNumber
- CB61873470
- Molecular Formula
- C14H18N4O3
- Formula Weight
- 290.31772
- MOL File
- 1189923-38-3.mol
Trimethoprim-d3 Property
- Melting point:
- 208-210°C
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Pale Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26119
- Product name
- Trimethoprim-d3
- Purity
- ≥99% deuterated forms (d1-d3)
- Packaging
- 500μg
- Price
- $178
- Updated
- 2024/03/01
- Product number
- 26119
- Product name
- Trimethoprim-d3
- Purity
- ≥99% deuterated forms (d1-d3)
- Packaging
- 1mg
- Price
- $336
- Updated
- 2024/03/01
- Product number
- 022396
- Product name
- Trimethoprim-d3
- Packaging
- 1mg
- Price
- $446
- Updated
- 2021/12/16
- Product number
- T795618
- Product name
- Trimethoprim-d3
- Packaging
- 10mg
- Price
- $1295
- Updated
- 2021/12/16
- Product number
- 7876DG
- Product name
- Trimethoprim-d3
- Packaging
- 1mg
- Price
- $472
- Updated
- 2021/12/16
Trimethoprim-d3 Chemical Properties,Usage,Production
Description
Trimethoprim-d3 is intended for use as an internal standard for the quantification of trimethoprim by GC- or LC-MS. Trimethoprim is a synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), which is necessary for the synthesis of purines, amino acids, and thymidylic acid. Trimethoprim shows prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Formulations containing trimethoprim, commonly used in combination with sulfamethoxazole to minimize acquired resistance, have been used in the treatment of urinary tract infections.
Chemical Properties
Off-White to Pale Yellow Solid
Uses
Trimethoprim-d3 (Major) is an antibacterial.
Uses
Deuterated Trimethoprim, an antibacterial