Reversan

Product Name: Reversan
CAS No.: 313397-13-6
Chemical Name: Reversan
Synonyms: CBLC4H10;Reversan;N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-;5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide;ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
CBNumber: CB61883226
Molecular Formula: C26H27N5O2
Formula Weight: 441.52
MOL File: 313397-13-6.mol

More

Less

Reversan Property

Melting point:: 176-180°C
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMSO: ≥8mg/mL at ~60°C
pka: 11.33±0.46(Predicted)
form: powder
color: faint yellow to yellow

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0173
Product name: Reversan
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $129
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0173
Product name: Reversan
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $519
Updated: 2024/03/01

Tocris

Product number: 3722
Product name: Reversan
Purity: ≥99%(HPLC)
Packaging: 50
Price: $952
Updated: 2021/12/16

Tocris

Product number: 3722
Product name: Reversan
Purity: ≥99%(HPLC)
Packaging: 10
Price: $227
Updated: 2021/12/16

Usbiological

Product number: 256447
Product name: Reversan
Packaging: 10mg
Price: $480
Updated: 2021/12/16

More

Less

Reversan Chemical Properties,Usage,Production

Uses

Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.

Biological Activity

Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin , vincristine and etoposide by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo . Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters.

storage

Store at -20°C

Reversan Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Reversan Suppliers

China 40 India 1 The Netherlands 1 United Kingdom 1 United States 6 USA 1 Global 50

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

313397-13-6, ReversanRelated Search:

N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide

Reversan

CBLC4H10

Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-

ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan

313397-13-6

C26H27N5O2

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals