ChemicalBook > CAS DataBase List > 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE

Product Name: 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
CAS No.: 86845-27-4
Chemical Name: 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
Synonyms: 5-BROMO-2-METHYLBENZOTRIFLUORIDE;4-BROMO-2-(TRIFLUOROMETHYL)TOLUENE;5-Bromo-2-methylbenzotrifluoride98%;5-Bromo-2-methylbenzotrifluoride 98%;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZEN;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE;4-bromo-1-methyl-2-(trifluoromethyl)benzene;Benzene,4-broMo-1-Methyl-2-(trifluoroMethyl)-;4-Methyl-3-(trifluoromethyl)bromobenzene, 97+%;4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE86845-27-4
CBNumber: CB6190972
Molecular Formula: C8H6BrF3
Formula Weight: 239.03
MOL File: 86845-27-4.mol

Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Property

Boiling point:: 181.8±35.0 °C(Predicted)
Density: 1 g/cm³
refractive index: 1.4870
storage temp.: 2-8°C
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C8H6BrF3/c1-5-2-3-6(9)4-7(5)8(10,11)12/h2-4H,1H3
InChIKey: IZFVIEYHUOUPPH-UHFFFAOYSA-N
SMILES: C1(C)=CC=C(Br)C=C1C(F)(F)F
CAS DataBase Reference: 86845-27-4(CAS DataBase Reference)

Less

Safety

Hazard Codes: F
Risk Statements: 10-36/37/38
Safety Statements: 16-26-36
RIDADR: 1993
Hazard Note: Flammable
HazardClass: IRRITANT
PackingGroup: III
HS Code: 2903998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TRC

Product number: B699063
Product name: 4-Bromo-2-(trifluoromethyl)toluene
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B699063
Product name: 4-Bromo-2-(trifluoromethyl)toluene
Packaging: 250mg
Price: $55
Updated: 2021/12/16

SynQuest Laboratories

Product number: 1800-B-59
Product name: 5-Bromo-2-methylbenzotrifluoride
Purity: 98%
Packaging: 1g
Price: $68
Updated: 2021/12/16

BroadPharm

Product number: BP-20386
Product name: 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
Purity: 96%
Packaging: 5G
Price: $70
Updated: 2021/12/16

BroadPharm

Product number: BP-20386
Product name: 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE
Purity: 96%
Packaging: 1g
Price: $20
Updated: 2021/12/16

Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Chemical Properties,Usage,Production

Synthesis

65934-74-9

86845-27-4

Under nitrogen protection, 2642.3 g of a 48% aqueous solution of hydrogen bromide was added to the reactor. The temperature of the system was adjusted to 30 °C, followed by the slow dropwise addition of 1760.0 g of a mixed solution of water and 880.0 g of acetic acid while stirring. Next, 880.0 g of 2-methyl-5-aminobenzotrifluoride (isomer content 0.037%, determined by gas phase area normalization) was added. After the dropwise addition, the reaction temperature was raised to 95 °C with continuous stirring for 30 min to obtain the corresponding hydrogen bromide salt solution. The reaction solution was cooled to 0 °C, at which temperature 1213.3 g of a 30% aqueous sodium nitrite solution was slowly added dropwise. After completion of the dropwise addition, the reaction was continued for 1.0 hour to ensure complete reaction. The prepared diazonium salt solution was slowly added dropwise at 65 °C to a pre-prepared mixture containing 360.4 g of copper bromide and 4997.0 g of 48% aqueous hydrogen bromide. A large amount of nitrogen release was observed during the reaction. After dropwise addition, stirring was continued for 1 hour to obtain a solution of 4-bromo-1-methyl-2-(trifluoromethyl)benzene. At the end of the reaction, the reaction solution was cooled to 20 °C, stirred for 1.0 h and left to stratify. 1046.0 g of the organic layer was separated and 3661.0 g of water was added and the pH was adjusted with 5.0% alkali metal hydroxide solution to 7. Subsequent steam distillation afforded 1032.0 g of a pale yellow 4-bromo-1-methyl-2-(trifluoromethyl)benzene product in 85.9% yield and 99.2% gas phase purity. Gas chromatographic analysis showed that the isomer content in the product was less than 0.1%.

References

[1] Patent: CN107915570, 2018, A. Location in patent: Paragraph 0057-0061; 0064-0067

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE Suppliers

Belgium 1 China 105 France 2 Germany 5 India 3 Italy 1 The Netherlands 1 United Kingdom 7 United States 18 Global 143

Shanghai Benso Pharmaceutical Technology Co., Ltd.

Tel: 15088289376
Email: 248775804@qq.com
Country: China
ProdList: 4995
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1930
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Changzhou Chemscaler Pharmtech Co., Ltd.

Tel: 0519-81096292 15312577869
Email: chemscaler@yahoo.com.cn
Country: China
ProdList: 311
Advantage: 60

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

AN PharmaTech Co Ltd

Tel: 86(21)68097365
Fax: 86(21)33321566
Email: sales@anpharma.net
Country: China
ProdList: 4891
Advantage: 55

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Shanghai WeiNie Chemical Technology Co., Ltd.

Tel: 15902145085
Fax: -
Email: 657990292@qq.com
Country: China
ProdList: 668
Advantage: 50

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

CHMA Chemical Technology (Shanghai) Co., Ltd

Tel: 021-61556450 15800904410
Fax: 021-61556450
Country: China
ProdList: 2832
Advantage: 58

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9942
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9853
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Dingfen Chemical Technology Co., Ltd.

Tel: 021-37590756
Fax: 021-57450128
Email: 373600283@qq.com
Country: China
ProdList: 4995
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8645
Advantage: 58

Less

View Lastest Price from 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE manufacturers

Career Henan Chemical Co

Product: 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE 86845-27-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: kg/T
Release date: 2019-12-18

86845-27-4, 4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENERelated Search:

2-Methylbenzotrifluoride Toluene 2-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE 2-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE 4-Methyl-2-(trifluoromethyl)bromobenzene, 97+% 3-METHYL-5-(TRIFLUOROMETHYL)BROMOBENZENE 2-Methyl-5-(trifluoromethyl)bromobenzene, 97+% 4-METHYL-2-(TRIFLUOROMETHYL)BROMOBENZENE

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE

4-BROMO-2-(TRIFLUOROMETHYL)TOLUENE

5-BROMO-2-METHYLBENZOTRIFLUORIDE

4-Methyl-3-(trifluoromethyl)bromobenzene, 97+%

5-Bromo-2-methylbenzotrifluoride 98%

5-Bromo-2-methylbenzotrifluoride98%

4-bromo-1-methyl-2-(trifluoromethyl)benzene

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZENE86845-27-4

Benzene,4-broMo-1-Methyl-2-(trifluoroMethyl)-

4-METHYL-3-(TRIFLUOROMETHYL)BROMOBENZEN

86845-27-4

Trifluoromethylbenzene serise