ChemicalBook > CAS DataBase List > 4-BUTOXYANILINE

4-BUTOXYANILINE

Product Name
4-BUTOXYANILINE
CAS No.
4344-55-2
Chemical Name
4-BUTOXYANILINE
Synonyms
AKOS BBB/082;AKOS BC-2572;4-Butoxyanline;4-BUTOXYANILINE;P-BUTOXYANILINE;p-butoxy-anilin;n-But-O-C6H4-NH2;p-Butyloxyaniline;4-N-BUTOXYANILINE;Aniline, p-butoxy-
CBNumber
CB6204785
Molecular Formula
C10H15NO
Formula Weight
165.23
MOL File
4344-55-2.mol
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4-BUTOXYANILINE Property

Melting point:
130-132 °C
Boiling point:
148-149 °C13 mm Hg(lit.)
Density 
0.992 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.538(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
clear liquid
pka
5.23±0.10(Predicted)
color 
Colorless to Brown
Specific Gravity
approximate 1
BRN 
2084421
CAS DataBase Reference
4344-55-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 4-butoxy-(4344-55-2)
EPA Substance Registry System
Benzenamine, 4-butoxy- (4344-55-2)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-28-36/37/39-45
RIDADR 
2810
WGK Germany 
3
RTECS 
BW9420000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
232343
Product name
4-Butoxyaniline
Purity
97%
Packaging
5g
Price
$51.2
Updated
2023/06/20
TCI Chemical
Product number
B1003
Product name
4-Butoxyaniline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
B1003
Product name
4-Butoxyaniline
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$96
Updated
2025/07/31
TRC
Product number
B701488
Product name
4-Butoxyaniline
Packaging
250mg
Price
$45
Updated
2021/12/16
Oakwood
Product number
001735
Product name
4-Butoxyaniline
Purity
97%
Packaging
1g
Price
$10
Updated
2021/12/16
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4-BUTOXYANILINE Chemical Properties,Usage,Production

Chemical Properties

CLEAR DARK BROWN LIQUID

Uses

4-Butoxyaniline was used in the preparation of:

  • bis-4-butoxyphenyl-4,4′-(2,2′-bipyridyl)carbamide
  • 1-(4-butoxyphenyl)-3-(6-methyl-3-oxo-2-phenyl-2,3-dihydropyridazin-4-yl)urea

General Description

4-Butoxyaniline undergoes low-pressure hydrogenation in the presence of rhodium on alumina to yield 4-butoxycyclohexylamine.

Synthesis

7244-78-2

4344-55-2

GENERAL METHOD: 1-butoxy-4-nitrobenzene (0.0270 mol) was dissolved in 70 mL of ethanol. Tin chloride (0.119 mol) was dissolved in 30 mL of ethanol and added dropwise to the reaction system. The reaction was stirred continuously at 80 °C for 2 hours. Upon completion of the reaction, the crude product was extracted twice with a solvent mixture of ethyl acetate/water (1:1, v/v) and 60 g of potassium carbonate was added to the aqueous phase to neutralize the acidic by-products. The organic phases were combined and the solvent was removed by evaporation under reduced pressure to give the yellow oily product 4-butoxyaniline. Yields ranged from 65% to 85%. For 4-butoxyaniline (3a), the 1H-NMR (DMSO-d6) data were as follows: δ 6.64 (d, 2H), 6.52 (d, 2H), 4.56 (s, 2H), 3.58 (t, 2H), 1.75 (m, 2H), 1.39 (m, 2H), 0.99 (t, 3H). The yield of 4-butoxyaniline under this experimental condition was 65%.

References

[1] Science China Chemistry, 2011, vol. 54, # 11, p. 1726 - 1734
[2] Molecules, 2017, vol. 22, # 8,
[3] Molecular Crystals and Liquid Crystals, 2009, vol. 510, p. 250 - 258
[4] Synthetic Communications, 1981, vol. 11, # 11, p. 925 - 930
[5] Journal of the American Chemical Society, 1922, vol. 44, p. 1744

4-BUTOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4344-55-2, 4-BUTOXYANILINERelated Search:


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