2-Aminobenzyl cyanide
- Product Name
- 2-Aminobenzyl cyanide
- CAS No.
- 2973-50-4
- Chemical Name
- 2-Aminobenzyl cyanide
- Synonyms
- o-Aminobenzyl cyanide;2-AMINOBENZYL CYANIDE;2-(Cyanomethyl)aniline;2-AMinobenzyl cyanide 97%;O-AMINOPHENYLACETONITRILE;2-AMINOPHENYLACETONITRILE;2-Aminobenzeneacetonitrile;Benzeneacetonitrile, 2-amino-;2-(2-azanylphenyl)ethanenitrile;2-AMINOBENZYL CYANIDE / 2-AMINOPHENYLACETONITRILE
- CBNumber
- CB6206936
- Molecular Formula
- C8H8N2
- Formula Weight
- 132.16
- MOL File
- 2973-50-4.mol
2-Aminobenzyl cyanide Property
- Melting point:
- 69-72 °C (lit.)
- Boiling point:
- 321°C
- Density
- 1.120±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO, Methanol
- pka
- 3.24±0.10(Predicted)
- form
- Powder
- color
- Off-white
- Exposure limits
- NIOSH: IDLH 25 mg/m3
- CAS DataBase Reference
- 2973-50-4(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 26-36/37/39-45
- WGK Germany
- 3
- HazardClass
- 6.1
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 349992
- Product name
- 2-Aminobenzyl cyanide
- Purity
- 97%
- Packaging
- 250mg
- Price
- $40.8
- Updated
- 2023/01/07
- Product number
- 349992
- Product name
- 2-Aminobenzyl cyanide
- Purity
- 97%
- Packaging
- 1g
- Price
- $58.6
- Updated
- 2023/01/07
- Product number
- A2997
- Product name
- 2-Aminobenzyl Cyanide
- Purity
- >98.0%(GC)(T)
- Packaging
- 200mg
- Price
- $48
- Updated
- 2025/07/31
- Product number
- A2997
- Product name
- 2-Aminobenzyl Cyanide
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $159
- Updated
- 2025/07/31
- Product number
- A596920
- Product name
- 2-Aminobenzyl cyanide
- Packaging
- 25g
- Price
- $400
- Updated
- 2021/12/16
2-Aminobenzyl cyanide Chemical Properties,Usage,Production
Chemical Properties
Brown Solid
Uses
2-Aminobenzyl cyanide may be used in the preparation of oxindole.
Synthesis
610-66-2
2973-50-4
General procedure for the synthesis of o-aminophenylacetonitrile from 2-nitrophenylacetonitrile: 2-nitrophenylacetonitrile (30 g, 185 mmol) and 10% palladium/carbon catalyst (2 g) were suspended in acetic acid (450 mL). The suspension was transferred to a Parr hydrogenation unit and the hydrogenation reaction was carried out at 30 psi hydrogen pressure and room temperature for 2 hours. Upon completion of the reaction, the reaction mixture was filtered through a Celite pad to remove the catalyst. The filtrate was concentrated to dryness under reduced pressure. The resulting residue was dissolved in ethyl acetate (250 mL) and washed sequentially with water (2 x 100 mL) and saturated sodium chloride solution (50 mL). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by column chromatography (100-200 mesh silica gel) using petroleum ether solution of 8% ethyl acetate as eluent to give o-aminophenylacetonitrile (13.5 g, 55% yield) as a white solid.1H NMR (CDCl3) δ ppm: 7.3-7.1 (m, 2H), 6.9-6.7 (m, 2H), 3.7 (br, 2H), 3.5 (s, 2H).
References
[1] Chemical and Pharmaceutical Bulletin, 1983, vol. 31, # 10, p. 3424 - 3445
[2] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 17
[3] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 34; 35
[4] Tetrahedron Letters, 2006, vol. 47, # 2, p. 159 - 162
[5] Journal of the American Chemical Society, 1950, vol. 72, p. 3047,3049
2-Aminobenzyl cyanide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Aminobenzyl cyanide manufacturers
- Product
- 2-Aminobenzyl cyanide 2973-50-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- 2-Aminobenzyl cyanide 2973-50-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-30